Results 31 to 40 of about 959,395 (302)

Can HRCT be used as a marker of airway remodelling in children with difficult asthma? [PDF]

, 2006
BACKGROUND: Whole airway wall thickening on high resolution computed tomography (HRCT) is reported to parallel thickening of the bronchial epithelial reticular basement membrane (RBM) in adult asthmatics. A similar relationship in children with difficult
Khoo L, Khoo, L, Payne, DN, Hansell DM, Bush, A, Saglani S, Saglani, S, Ujita, M, Jeffery, PK, Papaioannou G, Jeffery PK, Bush A, Papaioannou, G, Owens, C, Hansell, DM, Owens C, Payne DN, Owens, CM, Ujita M   +18 more
core   +1 more source

Randomized Controlled Trial of Fish Oil and Montelukast and Their Combination on Airway Inflammation and Hyperpnea-Induced Bronchoconstriction [PDF]

, 2010
Both fish oil and montelukast have been shown to reduce the severity of exercise-induced bronchoconstriction (EIB). The purpose of this study was to compare the effects of fish oil and montelukast, alone and in combination, on airway inflammation and ...
Louise A Turner, Turner Louise A., Mickleborough, Timothy D., Joel M Stager, Gregory S. Montgomery, Montgomery, Gregory, Tecklenburg-Lund, Sandra, Turner, Louise A., Montgomery, Gregory S., Alyce D. Fly, Joel M. Stager, Timothy D Mickleborough, Fly, Alyce D., Stager, Joel M., Fly, Alyce, Stager Joel M., Montgomery Gregory S., Mickleborough Timothy D., Timothy D. Mickleborough, Mickleborough, Timothy, Tecklenburg-Lund Sandra, Gregory S Montgomery, Stager, Joel, Louise A. Turner, Fly Alyce D., Turner, Louise, Sandra Tecklenburg-Lund, Alyce D Fly   +27 more
core   +2 more sources

Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD) [PDF]

, 2006
Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far.
David A Groneberg, Wagner, Ulrich, Fischer, Axel, Groneberg, Jan David Alexander, Groneberg David A, Welte, Tobias, Fehmann Hans-Christoph, Staats Petra, Axel Fischer, Welte Tobias, Fischer Axel, Ulrich Wagner, Tobias Welte, Fehmann, Hans-Christoph, Petra Staats, Staats, Petra, Hans-Christoph Fehmann, Wagner Ulrich   +17 more
core   +1 more source

Inflammation and Airway Reactivity

Experimental Lung Research, 1984
Sir John Floyer's preface to the Treatise of the Asthma, published in 1698, began as follows: Since the cure of the asthma is observed by all physicians, who have attempted the eradicating that chronical distemper, to be very difficult, and frequently unsuccessful: I may thence infer, that either the true nature of that disease is not thoroughly ...
J R, Snapper, K L, Brigham
openaire   +2 more sources

Immunoreactivity for interleukin-33 in allergic airway inflammation [PDF]

, 2015
Immunoreactivity for Interleukin-33 in Allergic Airway Inflammation,Cristan Herbert, Melissa M. Bunting, Neil Lambie, Paul S.
Kumar, RK ; https://orcid.org/, Herbert, C ; https://orcid.org/, Bunting, MM, Lambie, N, Thomas, PS ; https://orcid.org/   +4 more
core   +1 more source

PM2.5 Induced Nasal Mucosal Barrier Dysfunction and Epithelial–Mesenchymal Transition to Promote Chronic Rhinosinusitis Through IL4I1-AhR Signaling Pathway

Toxics
Environmental pollutants like PM2.5 contribute to chronic rhinosinusitis (CRS). The aryl hydrocarbon receptor (AhR), a contaminant sensor linked to tryptophan metabolites, is regulated by IL4I.
Yue Wang, Bowen Zheng, Panhui Xiong, Yijun Liu, Longlan Shu, Yang Shen, Tao Lu, Yucheng Yang   +7 more
doaj   +1 more source

Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite. [PDF]

PLoS ONE, 2013
Chronic allergic asthma is characterized by Th2-typed inflammation, and contributes to airway remodeling and the deterioration of lung function. However, the initiating factor that links airway inflammation to remodeling is unknown.
Zhuang-Gui Chen, Tian-Tuo Zhang, Hong-Tao Li, Fen-Hua Chen, Xiao-Ling Zou, Jing-Zhi Ji, Hong Chen   +6 more
doaj   +1 more source

Measurement of airway function using invasive and non-invasive methodsin mild and severe models for allergic airway inflammation in mice [PDF]

, 2014
In this study a direct comparison was made between non-invasive and non-ventilated unrestrained whole body plethysmography (Penh) (conscious animals) and the invasive ventilated lung resistance (RL) method (anaesthetized animals) in both mild and severe ...
Johan eGarssen, Kim eVerheijden, Frank A Redegeld, Verheijden, Kim A T, Paul A. J. Henricks, Garssen, Johan, Pharmacology, Gert Folkerts, Sub Immunopharmacology, Sub Airway in vivo Pharmacology, Kim A. T. Verheijden, Redegeld, Frank A., Henricks, Paul A J, Frank A. Redegeld, Paul eHenricks, Folkerts, Gert, Gert eFolkerts, UIPS - Utrecht Institute for Pharmaceutical Sciences, Johan Garssen   +18 more
core   +1 more source

Remodelling and Inflammation in Bronchial Asthma

European Journal of Inflammation, 2003
Chronic stable asthma is characterized by inflammation of the airway wall, with abnormal accumulation of basophils, eosinophils, lymphocytes, mast cells, macrophages, dendritic cells and myofibroblasts.
G. Riccioni, N. D'Orazio, R. Della Vecchia, T. Iezzi, C. Di Ilio   +4 more
doaj   +1 more source

Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose [PDF]

, 2013
Background Diabetes is a risk factor for respiratory infection, and hyperglycaemia is associated with increased glucose in airway surface liquid and risk of Staphylococcus aureus infection.
Garnett, James P, Tregoning, John S, Baines, DL, Baines, Deborah L, Knight, Gwenan M, Naik, S, Lindsay, JA, Tregoning, JS, Naik, Sonam, Garnett, JP, Baker, EH, Lindsay, Jodi A, Gill, S, Baker, Emma H, Gill, Simren, Knight, GM   +15 more
core   +1 more source