Obesity-induced asthma: Role of free fatty acid receptors
Japanese Dental Science Review, 2019 Obesity is a major risk factor for the development of asthma, and worsens the key features of asthma including airway hyperresponsiveness, inflammation, and airway remodeling.
Kentaro Mizuta +4 more
doaj +1 more source
Acute effects of inspiratory pressure threshold loading upon airway resistance in people with asthma [PDF]
, 2009 This is the post-print version of the final paper published in Respiratory Physiology & Neurobiology. The published article is available from the link below.
How, Stephen C +4 more
core +1 more source
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Hepatology, EarlyView., 2022 Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source
CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms
Mediators of Inflammation, 2018 Asthma is an inflammatory disease in which proinflammatory cytokines have a role in inducing abnormalities of airway smooth muscle function and in the development of airway hyperresponsiveness.
Deepak A. Deshpande +6 more
doaj +1 more source
Dandelion extract relaxes mouse airway smooth muscle by blocking VDLCC and NSCC channels
Cell & Bioscience, 2020 Background Asthma is one of the main intractable diseases recognized by the international medical community. The current widely used bronchodilators for asthma—β2-adrenal receptor agonists—have limited therapeutic effects, necessitating the development ...
Ping Zhao +8 more
doaj +1 more source
Multum non multa: airway distensibility by forced oscillations
Monaldi Archives for Chest Disease, 2016 Airway distensibility although appears to be unaffected by airway smooth muscle tone probably related to airway remodelling, after bronchodilator treatment is significantly increased in subjects with asthma.
Charalampos Mermigkis +2 more
doaj +1 more source
Airway obstruction in asthma: does the response to a deep inspiration matter?
Respiratory Research, 2001 Airway hyperresponsiveness in asthma may not be a problem of too much airway smooth muscle strength. Rather, it may be a problem of too little of the factors that oppose muscle shortening.
Fredberg Jeffrey J
doaj +1 more source
Airway Smooth Muscle and Asthma
Allergology International, 2006 The airway smooth muscle is the key determinant of airway narrowing in asthma but its function in the absence of disease is unknown. Evidence for an intrinsic abnormality in the muscle in asthma is only just emerging.
Brian G. Oliver, Judith L. Black
doaj +1 more source
Airway smooth muscle cells respond directly to inhaled environmental factors
Swiss Medical Weekly, 2010 A misled or overreacting immune response is assumed to be the major cause of the most prevalent chronic inflammatory lung diseases, asthma and chronic obstructive pulmonary disease (COPD).
Michael Roth, Michael Tamm
doaj +1 more source
Induction and regulation of matrix metalloproteinase-12in human airway smooth muscle cells
Respiratory Research, 2005 Background The elastolytic enzyme matrix metalloproteinase (MMP)-12 has been implicated in the development of airway inflammation and remodeling.
Papi Alberto +8 more
doaj +1 more source