Results 151 to 160 of about 614,051 (372)

Electron asymmetries in the photoionization of chiral molecules: possible astrophysical implications

Advances in Physics: X, 2018
Photoelectron circular dichroism (PECD) is an intense orbital-specific chiroptical effect observed as asymmetries in the angular distribution of photoelectrons produced by photoionization of randomly oriented pure enantiomers with circularly polarized ...
Rim Hadidi, Dusan K. Bozanic, Gustavo A. Garcia, Laurent Nahon   +3 more
doaj   +1 more source

Generating Minimum Free Energy Paths With Denoising Diffusion Probabilistic Models [PDF]

arXiv
A method combining denoising diffusion probabilistic models (DDPMs) with the string method is presented to generate minimum free energy paths between metastable states in molecular systems. It has been demonstrated in recent work that DDPMs at low noise levels can approximate the gradient of the potential of mean force, allowing efficient sampling of ...
arxiv  

Constant enzymatic in situ production of H₂O₂ for an Unspecific Peroxygenase by an L‐amino acid oxidase

Advanced Synthesis &Catalysis, Accepted Article.
Unspecific Peroxygenases have been the subject of a lot of research in the recent past as they offer opportunities for green hydroxylation reactions using hydrogen peroxide (H₂O₂) as donor. A striking problem of UPOs is their low stability against their own co‐substrate H₂O₂.
Simon Last, Tobias Heinks, Niklas Dietz, Simon Koopmeiners, Gabriele Fischer von Mollard, Martin Weissenborn, Jan von Langermann   +6 more
wiley   +1 more source

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

Nature, 2016
C. Sousa, Douglas E. Biancur, Xiaoxu Wang, Christopher J. Halbrook, M. Sherman, Li Zhang, Daniel M. Kremer, R. Hwang, Agnes K. Witkiewicz, H. Ying, J. Asara, Ronald M. Evans, L. Cantley, C. Lyssiotis, Alec C. Kimmelman   +14 more
semanticscholar   +1 more source

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

Advanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos, Aleksandra Rudzka, Anna Hoser, Tamara Reiter, Wolfgang Kroutil, Paweł Borowiecki   +5 more
wiley   +1 more source

Second‐Generation Organic Nanozyme for Effective Detection of Agricultural Herbicides

Advanced Sustainable Systems, EarlyView.
A sustainable organic nanozyme‐based colorimetric sensing platform is developed for detecting toxic agrichemicals. The second‐generation EU nanozyme, synthesized via a modified self‐assembly process, exhibits peroxidase‐like activity, degradability, and biocompatibility.
Dong Hoon Lee, Mohammed Kamruzzaman
wiley   +1 more source

Catabolism of germinant amino acids is required to prevent premature spore germination in Bacillus subtilis

mBio
Spores of Bacillus subtilis germinate in response to specific germinant molecules that are recognized by receptors in the spore envelope. Germinants signal to the dormant spore that the environment can support vegetative growth, so many germinants, such ...
Iqra R. Kasu, Octavio Reyes-Matte, Alejandro Bonive-Boscan, Alan I. Derman, Javier Lopez-Garrido   +4 more
doaj   +1 more source

ALANINE: A Novel Decentralized Personalized Federated Learning For Heterogeneous LEO Satellite Constellation [PDF]

arXiv
Low Earth Orbit (LEO) satellite constellations have seen significant growth and functional enhancement in recent years, which integrates various capabilities like communication, navigation, and remote sensing. However, the heterogeneity of data collected by different satellites and the problems of efficient inter-satellite collaborative computation ...
arxiv  

Unit-cell dimensions and space groups of synthetic peptides. II. Glycyl-L-alanine, glycyl-L-alanine hydrochloride, glycyl-L-analine hydrobromide and glycyl-L-tryptophane [PDF]

, 1953
T.C. Tranter
openalex   +1 more source

Hydroxyapatite Binding Peptide Lipid Nanoparticles for Biomimetic mRNA Delivery to Bone

Advanced Therapeutics, EarlyView.
Targeted delivery of therapeutic mRNA to peripheral tissues, including bone, is currently challenging. In the current work, a hydroxyapatite binding peptide (HABP) is conjugated to mRNA lipid nanoparticles (LNPs). HABP‐LNPs delivered systemically are demonstrated to reduce transfection in the liver and improve transfection in the femurs of mice ...
Joshua A. Choe, Jena E. Moseman, Jamie M. Jones, Jacobus C. Burger, Ashley M. Weichmann, Douglas G. McNeel, William L. Murphy   +6 more
wiley   +1 more source