Results 191 to 200 of about 814,837 (335)

Purification and characterization of N -acetylmuramyl- l -Alanine amidase from human plasma using monoclonal antibodies

, 1996
Maarten A. Hoijer, Marie‐José Melief, Wolfgang Keck, M. P. Hazenberg   +3 more
openalex   +2 more sources

Alanine-scanning Mutagenesis of a C-terminal Ligand Binding Domain of the Insulin Receptor α Subunit [PDF]

, 1996
Dennis C. Mynarcik, Gui Qin Yu, Jonathan Whittaker   +2 more
openalex   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Design and rationale for a pilot trial of D-alanine supplementation to reduce the triglyceride to high-density lipoprotein cholesterol ratio in patients with chronic kidney disease. [PDF]

BMC Nephrol
Matsui M, Nishimoto M, Uemura T, Kitamura S, Tato W, Tsushima H, Kosugi T, Eriguchi M, Samejima KI, Mita M, Kasahara M, Tsuruya K.   +11 more
europepmc   +1 more source

Suppression of Methotrexate-Induced Elevations in the Serum Alanine Aminotransferase Level of Patients with Rheumatoid Arthritis Who Had Prior Hepatitis B Infection

, 2018
Osamu Noguchi, Yukio Nakamura, Hiroyuki Kato   +2 more
openalex   +2 more sources

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates. [PDF]

Nat Commun
Ochtrop P, Jagtap AP, Felber JG, Vogt S, Herterich S, Mai I, Cyprys P, Schmitt S, Payer S, Kitowski A, Wunder S, Machui P, Brandmeier J, Leonardi N, Poliak E, Hackenberger CPR, Marcq O, Schumacher D, Helma J, Vogl AM, Kasper MA.   +20 more
europepmc   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Poolside Activity Measurement of Cobalt Target

Journal of Isotopes
To obtain cobalt target activity data after a cycle of irradiation in a pressurized water reactor, the cobalt target dose distribution was measured underwater using alanine dosimeters.
YIN Zhenguo1, LIAN Qi2, ZHANG Ping1, XU Bei2, WANG Mingming2, FENG Wuzhou1, YAN Tianyu1
doaj  

Structural Insights into the <i>Staphylococcus aureus</i> DltC-Mediated D-Alanine Transfer. [PDF]

Biomolecules
Jeon H, Lee H, Song C, Lee IG.
europepmc   +1 more source