Autism spectrum disorder (ASD) is a neurodevelopmental pathology characterized by the impairment of social interaction, difficulties in communication, and repetitive behaviors. Alterations in the metabolism of amino acids have been reported. We performed
Mariem Chamtouri+7 more
doaj +1 more source
Implementing Dimer Metadynamics using GROMACS [PDF]
We develop a Gromacs implementation of Dimer Metadynamics[JCTC 13, 425 (2017)] for enhanced sampling through artificial delocalization effects. This implementation is based entirely on a Plumed collective variable developed for this purpose, the fine tuning of Gromacs input parameters, modified forcefields and custom non-bonded interactions.
arxiv +1 more source
The upper normal limit of serum alanine aminotransferase in Golestan Province, Northeast Iran [PDF]
Background: The objective of this study was to determine the upper normal limit of serum alanine aminotransferase level in a population-based study in Golestan Province, northeast Iran.
Amini, S.+5 more
core +6 more sources
Can Ammonium Tartrate Replace Alanine in EPR Radiation Dosimetry?
EPR, which is characterized by the non-destructive evaluation of radiation-induced radicals, is one of the most recent and accurate techniques for radiation dose measurements.
Ahmed Mohamed Maghraby+2 more
doaj +1 more source
Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer.
Pancreatic ductal adenocarcinoma (PDAC) evolves a complex microenvironment comprised of multiple cell types, including pancreatic stellate cells (PSCs).
Seth J. Parker+17 more
semanticscholar +1 more source
Relationship of fetal alanine uptake and placental alanine metabolism to maternal plasma alanine concentration [PDF]
Uterine and umbilical uptakes of alanine (Ala) were measured in 10 ewes before (control) and during intravenous infusion of Ala, which increased maternal arterial Ala concentration from 115 ± 14 to 629 ± 78 μM ( P < 0.001). In 8 of these ewes, placental Ala fluxes were traced by constant intravenous infusion ofl-[3,3,3-2H3]Ala in the mother andl-[1-
Michelle Timmerman+5 more
openaire +3 more sources
Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers
Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria. Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference can be exploited to detect living bacteria in vivo.
Matthew F. L. Parker+12 more
semanticscholar +1 more source
Effects of beta-alanine supplementation on brain homocarnosine/carnosine signal and cognitive function: an exploratory study [PDF]
Objectives: Two independent studies were conducted to examine the effects of 28 d of beta-alanine supplementation at 6.4 g d-1 on brain homocarnosine/carnosine signal in omnivores and vegetarians (Study 1) and on cognitive function before and after ...
A Boldyrev+62 more
core +6 more sources
Fiber Length of Eri Silk Cocoons and Influence of Staple Cutting during Spinning Preparatory Process
The range of single fiber length in both white and brick red eri cocoons is very high due to inactivity of Filipi’s gland of silkworm along with open structure of cocoons’ shells.
Debasis Chattopadhyay+2 more
doaj +1 more source
Surface Chirality in Rotational Magnetoelectrodeposition of Copper Films
Chiral surface formation was investigated in rotational magnetoelectrodeposition (RMED) of copper films, where an electrochemical cell was rotated in magnetic fields.
Iwao Mogi+3 more
doaj +1 more source