Synthesis, Structural Characterization, and DFT Studies of Fe(III), Co(II), and Ni(II) Mixed-Ligand Complexes With Albendazole and Nifuroxazide With Molecular Docking Against Respiratory Pathogen Targets. [PDF]
Bioinorg Chem ApplIn this study, the structural, electronic, and biological characteristics of newly synthesized transition metal complexes FeABNF, CoABNF, and NiABNF, resulting from the chelation compounds albendazole (AB) and nifuroxazide (NF), were studied. The synthesized compounds were found to have excellent yields with high percentage yields (∼80%).
S YA, El-Lateef HMA, Khalaf MM, Abdou A.
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PLoS Pathogens, 2022 Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ).
Edar O. Pech-Santiago +7 more
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Validation of high performance liquid chromatography coupled to mass spectrometry to determine albendazole sulfoxide in human plasma [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2022 Context: Albendazole is used in the treatment of cysticercosis and hydatid disease, and its prolonged administration can generate adverse effects attributed to the active metabolite, albendazole sulfoxide (ABZSO), whose measurement requires validated ...
Jaime Rosales-Rimache +6 more
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SCOLICIDAL EFFICACY OF SELENIUM NANOPARTICLES AGAINST PROTOSCOLECES OF HYDATID CYST [PDF]
Journal of the Egyptian Society of Parasitology, 2018 The hydatid disease known as hydatidosis or echinococcosis is a cyclozoonotic disease widely distributed in the viscera and other organs of humans and animals.
SALWA OSHIBA, AMERA AFIFI
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Analysis of the effect of in vitro dissolution on the pharmacokinetics of albendazole
Brazilian Journal of Pharmaceutical Sciences, 2023 Albendazole is an anthelmintic drug commonly used in parenchymal neurocysticercosis and cystic echinococcosis. The aim of this study was to explore whether disparities in the dissolution profiles of albendazole products lead to significant differences in
Nelly Castro +5 more
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Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. [PDF]
PLoS ONE, 2014 Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. No method is currently available for measuring albendazole and its metabolites in silkworm hemolymph.
Li Li +5 more
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Nanocrystal Suspensions for Enhancing the Oral Absorption of Albendazole
Nanomaterials, 2022 Albendazole (ABZ), an effective benzimidazole antiparasitic drug is limited by its poor solubility and oral bioavailability. In order to overcome its disadvantages, ABZ nanocrystals were prepared using a novel bottom-up method based on acid-base ...
Zhiwei Liang +4 more
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Efficacies of Albendazole Sulfoxide and Albendazole Sulfone against In Vitro-Cultivated Echinococcus multilocularis Metacestodes [PDF]
Antimicrobial Agents and Chemotherapy, 1999 ABSTRACT The metacestode stage of Echinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), a parasitic disease affecting the liver, with occasional metastasis into other organs.
Ingold, K +5 more
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Molecules, 2023 Albendazole is the preferred deworming drug and has strong insecticidal effects on human and animal helminth parasites, showing remarkable activity against hepatocellular carcinoma and colorectal cancer cells.
Yili Ding +4 more
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Penetration of albendazole sulphoxide into hydatid cysts. [PDF]
Gut, 1987 The penetration of albendazole sulphoxide, the principal metabolite of albendazole into hydatid cysts (E granulosus) was measured by means of in vitro animal and clinical studies. The drug freely diffuses across the parasitic membranes. Cyst/serum concentrations of 22% were achieved in patients, longer pre-operative therapy produced higher ...
MORRIS, DL +4 more
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