Results 41 to 50 of about 1,204 (151)

Effect of Sambucus Ebulus Extract and Erythromycin on Albendazole-Induced Histomorphometric Changes in Placenta of Rat

مجله دانشکده پزشکی اصفهان, 2018
Background: There are some reports that albendazole passes placenta and causes disorders in fetus. Besides, there is some evidence that the effect apparently is related to its active metabolite, albendazole sulfoxide.
Mahmood Khaksary-Mahabady, Reza Ranjbar, Hossein Najafzadeh-Varzi, Hasan Morovvati, Elnaz Lak   +4 more
doaj   +1 more source

In vitro effects of tropisetron and granisetron against Echinococcus granulosus (s.s.) protoscoleces by involvement of calcineurin and calmodulin

Parasites & Vectors, 2021
Background Cystic echinococcosis (CE) is a disease caused by the larval stage of Echinococcus granulosus sensu lato  (s.l.). The treatment of CE mainly relies on the use of benzimidazoles, which can commonly cause adverse side effects.
Mohammad Reza Shiee, Eshrat Beigom Kia, Farzaneh Zahabiun, Mahmood Naderi, Elahe Motevaseli, Shahram Nekoeian, Majid Fasihi Harandi, Ahmad Reza Dehpour   +7 more
doaj   +1 more source

Probing Cinnamamides and Benzamides as Anthelmintics: Discovery of Potent Drug‐Like Agents Against Angiostrongylus cantonensis

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Cynnamoyl benzylpiperazine was identified as drug‐like derivative of cinnarizine with anthelmintic activity against A. cantonensis. In this work, 15 out of 31 derivatives showed improved anthelmintic activity with increased solubility. A SAR study was carried out to determine the molecular features involved in such effect.
Bruna L. Lemes, Mariana A. Siegl‐Breno, Marina T. Varela, Flavia B. Lopes, Mikaelly K. Silva‐Nunes, Thaiane D. Santos, Lucas Fukui‐Silva, Daniel B. Roquini, Vinicius G. Maltarollo, Josué de Moraes, João Paulo S. Fernandes   +10 more
wiley   +1 more source

Solution‐Processed Nickel Oxide as Efficient Hole Transport Layers in Inverted Perovskite Solar Cells

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This review summarizes recent advances in four mainstream solution‐based techniques for synthesizing NiOx hole‐transport layers for high‐performance perovskite photovoltaic cells, and highlights the key challenges and future prospects for achieving high efficiency, long‐term stability, and low‐cost perovskite photovoltaic technologies toward ...
Zheng Wu, Zeliang Qiu, Yuxin Tao, Yuyang Qiu, Yuwei Duan, Jianxing Xia, Feng Li, Qiang Peng   +7 more
wiley   +1 more source

Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice. [PDF]

PLoS Neglected Tropical Diseases, 2015
This study aimed to investigate the pharmacology and anti-parasitic efficacy of albendazole-chitosan microspheres (ABZ-CS-MPs) for established intraperitoneal infections of Echinococcus multilocularis metacestodes in an experimental murine model.
Maitiseyiti Abulaihaiti, Xiang-Wei Wu, Lei Qiao, Hai-Long Lv, Hong-Wei Zhang, Nasrul Aduwayi, Yan-Jie Wang, Xin-Chun Wang, Xin-Yu Peng   +8 more
doaj   +1 more source

Pharmacological characterization of geraniol in sheep and its potential use in the control of gastrointestinal nematodes

Veterinary and Animal Science, 2022
Geraniol (GNL) was effective against gastrointestinal nematodes in vitro; nevertheless, the anthelmintic effect of phytochemicals combined with synthetic drugs has been little explored in vivo.
María Victoria Miró, Livio Martins Costa-Júnior, Luis Ignacio Alvarez, Carlos Lanusse, Guillermo Virkel, Adrián Lifschitz   +5 more
doaj   +1 more source

Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva, Felipe C. R. de Souza, Camila S. Amorim, Josué de Moraes, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

Comprehensive Evaluation of Methanolic Fruits Extract of Jatropha gossypifolia L.: Neuropharmacological, Cytotoxic, Anthelmintic, GC–MS Profiling, and Molecular Docking Studies

Pharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
The anxiolytic properties of the methanolic fruit extract of Jatropha gossypifolia (JGF‐ME) were investigated using the Elevated Plus Maze (EPM), Hole Board Test (HBT), and Light–Dark Box Test (LDT), while its antidepressant potential was examined through the Forced Swimming Test (FST) and Tail Suspension Test (TST).
Md. Arafat, Nusrat Jahan Moon, Mahathir Mohammad, Md. Jahirul Islam Mamun, Jannatul Naima Meem, Md. Hossain Rasel, Borhan Uddin, Md. Safayat Hossen Momen, Md. Liakot Ali, Neamul Hoque, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Immobilization of cytochrome P450 enzymes onto magnetic beads: An approach to drug metabolism and biocatalysis

Talanta Open, 2023
Cytochrome P450 (CYP, P450) presents a wide range of applicability in drug metabolism studies and in biocatalysis as a great alternative to synthesizing compounds. Nonetheless, their lack of stability is one of their major drawbacks.
Izadora Liranço Furlani, Regina Vincenzi Oliveira, Quezia Bezerra Cass   +2 more
doaj   +1 more source

Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)

World Journal of Gastroenterology, 2009
To establish which scolicidal agents are superior and more suitable for regular use.Echinococcus granulosus protoscoleces were obtained from 25 patients with liver hydatid cysts. Various concentrations of albendazole sulfone, albendazole sulfoxide, and albendazole sulfone and albendazole sulfoxide mixed together in concentrations of 50 microg/mL, and H(
Gokhan, Adas, Soykan, Arikan, Ozgur, Kemik, Ali, Oner, Nilgun, Sahip, Oguzhan, Karatepe   +5 more
openaire   +2 more sources