Results 91 to 100 of about 1,382,004 (349)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Efficacy of albumin use in decompensated cirrhosis and real‐world adoption in Australia
JGH OpenThe current treatment approach to patients with liver cirrhosis relies on the individual management of complications. Consequently, there is an unmet need for an overall therapeutic strategy for primary and secondary prevention of complications.
Eric Kalo +16 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The Relationships among Serum Glucose, Albumin Concentrations and Carotid Atherosclerosis in Men with Spinal Cord Injury [PDF]
, 2010 Limited information is available that examines the interrelationships between glucose tolerance, serum albumin, subclinical inflammation, and carotid atherosclerosis (CA) in patients with spinal cord injury (SCI).
WANG, YEN-HO;CHEN, SSU-YUAN;WANG, TZUNG -DAU;HWANG, BAO-SHOW;HUANG, TIEN-SHANG;SU, TA-CHEN +1 more
core +1 more source
Frontiers in MedicineBackgroundIdiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by chronic inflammation and progressive fibrosis. The blood urea nitrogen-to-albumin ratio (BAR) is a comprehensive parameter associated with inflammation status;
Shaobo Ge +10 more
doaj +1 more source
Frontiers in Neurology, 2019 Aim: The purpose of the present study was to determine if C-reactive protein (CRP)/albumin ratio was associated with disease severity and unfavorable outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH).Methods: One hundred and twenty-three
Dingding Zhang +8 more
doaj +1 more source
Albumin-based nanoparticles: a promising strategy to overcome cancer drug resistance
Cancer Drug Resistance, 2020 Circumvention of cancer drug resistance is one of the major investigations in nanomedicine. In this regard, nanotechnology-based drug delivery has offered various implications.
Islam A Hassanin, Ahmed O. Elzoghby
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Surface imprinted beads for the recognition of human serum albumin [PDF]
, 2007 The synthesis of poly-aminophenylboronic acid (ABPA) imprinted beads for the recognition of the protein human serum albumin (HSA) is reported. In order to create homogeneous recognition sites, covalent immobilisation of the template HSA was exploited.
Bossi, Alessandra, +13 more
core +1 more source
Frontiers in Ecology and EvolutionThis study compares the decision-making processes and workflows of complex and simple wildlife forensic cases at the Wyoming Game and Fish Wildlife Forensic Laboratory.
Kimberly M. Frazier, Tasha L. Bauman
doaj +1 more source