Results 81 to 90 of about 1,507,102 (353)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Electrophoretic Analysis of Blood Serum Proteins in Three Species of Water Snakes (Genus Nerodia) [PDF]

open access: yes, 1979
Serum from three species of water snakes (Nerodia rhombifera, N. erythrogaster and N. fasciata) from one geographic region was analyzed electrophoretically on cellulose acetate, and anodic mobility and relative concentration of the fractions were ...
Garnett, Phyllis J.
core   +2 more sources

A mathematical model for fluid-glucose-albumin transport in peritoneal dialysis

open access: yes, 2013
A mathematical model for fluid and solute transport in peritoneal dialysis is constructed. The model is based on a three-component nonlinear system of two-dimensional partial differential equations for fluid, glucose and albumin transport with the ...
Cherniha, R.   +2 more
core   +1 more source

Effects of caffeic acid and bovine serum albumin in reducing the rate of development of rancidity in oil-in-water and water-in-oil emulsions [PDF]

open access: yes, 2011
The antioxidant properties of caffeic acid and bovine serum albumin in oil-in-water and water-in-oil emulsions were studied. Caffeic acid (5 mmol/kg emulsion) showed good antioxidant properties in both 30% sunflower oil-in-water (OW) and 20% water-in ...
Conde, Enma   +3 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Can Serum Albumin Level At Diagnosis Be A Guide for Clinical Features, Time to Treatment, and Response in Patients with Follicular Lymphoma?

open access: yesNamık Kemal Tıp Dergisi
Aim: The aim of the present study was to determine the association between serum albumin level and treatment demand, time to treatment and treatment response in patients with follicular lymphoma (FL).
Abdulkadir KARIŞMAZ   +4 more
doaj   +1 more source

Keefektifan ekstra putih telur terhadap peningkatan albumin dan penurunan IL-1β pada pasien tuberkulosis dengan hipoalbuminemia

open access: yesJurnal Gizi Klinik Indonesia, 2014
Background: Tuberculosis (TB) is world health problem which still needs attention. Recently, Indonesia ranks the third in TB prevalence after India and China.
Agus Prastowo   +3 more
doaj   +1 more source

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development [PDF]

open access: yes, 2017
Acknowledgments: The authors would like to acknowledge the funding support for this work from Scottish Enterprise [VNAR_001(2012)] and the Biotechnology and Biological Sciences Research Council (BB/K010905/1).Peer reviewedPublisher ...
Andrew J. Porter   +11 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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