Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata+6 more
wiley +1 more source
Crystal Structure and Biophysical Analysis of Furfural-Detoxifying Aldehyde Reductase from Clostridium beijerinckii. [PDF]
Scott AF+6 more
europepmc +1 more source
Summary Flower scent is a crucial determiner in pollinator attraction and a significant horticultural trait in ornamental plants. Orchids, which have long been of interest in evolutionary biology and horticulture, exhibit remarkable diversity in floral scent type and intensity. However, the mechanisms underlying floral scent biosynthesis and regulation
Mengling Tu+7 more
wiley +1 more source
One can’t stand on its own: Are non-luminescence traits necessary for V. fischeri colonization of E. scolopes? [PDF]
Vibrio fischeri and Euprymna scolopes squid establish mutualistic symbiosis and select for each other in the natural environment. V. fischeri provides bioluminescent camouflage for E. scolopes while E. scolopes provides nutrients for V. fischeri.
Liu, Feier
core +1 more source
Elucidating the enzyme network driving Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum
Schematic representation of Amaryllidaceae alkaloid biosynthesis in Leucojum aestivum. Norbelladine synthase (LaNBS) and noroxomaritidine/norcraugsodine reductase (LaNRII) catalyze the condensation of tyramine and 3,4‐dihydroxybenzaldehyde to form norbelladine, which is subsequently O‐methylated by norbelladine‐4′‐O‐methyltransferase (LaN4′OMT ...
Basanta Lamichhane+6 more
wiley +1 more source
Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. [PDF]
Epoxides are highly useful synthons and biosynthons for the construction of complex natural products during total synthesis and biosynthesis, respectively.
Garcia-Borràs, Marc+8 more
core
Plant genetic transformation: achievements, current status and future prospects
Summary Regeneration represents a fundamental biological process wherein an organism's tissues or organs repair and replace themselves following damage or environmental stress. In plant systems, injured tree branches can regenerate adventitious buds and develop new crowns through propagation techniques like cuttings and canopy pruning, while transgenic
Peilin Wang+6 more
wiley +1 more source
In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes
The drug candidate and psychedelic mushroom product psilocybin was produced by multienzyme‐charged beads in a biocatalytic cell‐free approach. Using immobilized fungal indolethylamine biosynthetic and additional bacterial enzymes, these beads turned over 4‐hydroxy‐l‐tryptophan to psilocybin.
Tim Schäfer+7 more
wiley +1 more source
Toward aldehyde and alkane production by removing aldehyde reductase activity in Escherichia coli. [PDF]
Rodriguez GM, Atsumi S.
europepmc +1 more source
The aldehyde dehydrogenase superfamilies: correlations and deviations in structure and function. [PDF]
Heider J, Hege D.
europepmc +1 more source