Results 231 to 240 of about 424,465 (437)

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

Advanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang, Yunxing Huang, Yin Tong, Kenneth Tsz Chun Ng, Jiangwen Zhang   +4 more
wiley   +1 more source

<i>Z</i>-Selective Synthesis of Trisubstituted Alkenes by the HWE Reaction Using Modified Still-Gennari Type Reagents. [PDF]

J Org Chem
Janicki I.
europepmc   +1 more source

hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation

Advanced Science, EarlyView.
This article addresses the absence of zonation features in current organoid models by co‐culturing human embryonic stem cell‐derived hepatocytes with liver sinusoidal endothelial cells exhibiting distinct zonal characteristics. It demonstrates that differential WNT2 signaling from endothelial cells modulates hepatocyte zonation and metabolic functions,
Yuying Zhang, Chenyan Huang, Lei Sun, Lyu Zhou, Yudi Niu, Kaini Liang, Bingjie Wu, Peng Zhao, Zhiqiang Liu, Xiaolin Zhou, Peng Zhang, Jianchen Wu, Jie Na, Yanan Du   +13 more
wiley   +1 more source

Soy protein selectively accumulates formaldehyde. [PDF]

Sci Rep
Yamada M, Uchida M, Yamada T.
europepmc   +1 more source

Ueber Condensation einiger Aldehyde mit Methyl‐ und Aethyl‐Amin und die Reduction der Condensationsproducte [PDF]

, 1902
Carl Andree
openalex   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Recent advances in catalytic approaches for the synthesis of 3-substituted indoles: mechanisms and strategies. [PDF]

RSC Adv
Abdu Musad Saleh E, Firoz KH, Uthirapathy S, Asiri M, M M R, Kundlas M, Kumar VR, Ray S, Sadeq Yousif Z, Ridha-Salman H.   +9 more
europepmc   +1 more source

Polarography of fragrant aldehydes

, 1957
Hisashi Sato
openalex   +2 more sources

XIX. Ueber die Einwirkung von Diacetonitril auf Aldehyde [PDF]

, 1897
E. Mohr
openalex   +1 more source

Thermally Reconstructed Ru/La‐Co3O4 Nanosheets with Super Thermal Stability for Catalytic Combustion of Light Hydrocarbons: Induced Surface LaRuO3 Active Phase

Advanced Science, EarlyView.
The high‐temperature induced the exsolution of La from La‐Co3O4 lattice and facilitated the in situ formation of highly active LaRuO3 perovskite through a solid‐phase reaction with surface RuOx. This process significantly enhanced the thermal and hydrothermal stability of Ru/La‐Co3O4 for light hydrocarbons (LHs) oxidation, providing an innovative ...
Biao Gao, Wei Deng, Hangqi Xia, Kai Shan, Li Wang, Boyuan Qiao, Qiang Niu, Aiyong Wang, Yun Guo, Wangcheng Zhan, Yanglong Guo, Qiguang Dai   +11 more
wiley   +1 more source