Results 301 to 310 of about 424,465 (437)

CCDC80 Protects against Aortic Dissection and Rupture by Maintaining the Contractile Smooth Muscle Cell Phenotype

open access: yesAdvanced Science, EarlyView.
Aortic dissection (AD) is accompanied by a decrease in CCDC80 in vascular smooth muscle cells (VSMCs). CCDC80 can interact with JAK2, and VSMC‐specific CCDC80 deficiency accelerates the progression of AD by activating the JAK2/STAT3 pathway involved in regulating the phenotype switching and function of VSMCs.
Qingqing Xiao   +18 more
wiley   +1 more source

Highly Diastereo- and Enantioselective Allylboration of Aldehydes using alpha-Substituted Allyl/Crotyl Pinacol Boronic Esters via in Situ Generated Borinic Esters [PDF]

open access: yes, 2013
Althaus M.   +60 more
core   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu   +13 more
wiley   +1 more source

Hydrolyzable Bio‐Based Bisphenols Enabled by the Tishchenko Reaction for Polyurethane Vitrimers with Closed‐Loop Recyclability

open access: yesAdvanced Science, EarlyView.
This study employs the Tishchenko coupling reaction to obtain bio‐based bisphenols containing degradable ester bonds with 100% atom utilization. Based on these bio‐based bisphenols, a fully bio‐based polyurethane Covalent Adaptable Networks are constructed, while simultaneously endowing the material with closed‐loop recyclability, degradability, and ...
Jiewen Wang   +7 more
wiley   +1 more source

Sustainable Development of High‐performance Poly(ester‐imine) Biobased Thermosets

open access: yesAdvanced Science, EarlyView.
Schiff‐based epoxy monomers derived from renewable natural resources are used to design robust structures by cross–linking with bio‐anhydrides. The resulting eco‐friendly, high‐performance thermosets feature two cleavable bonds, offering versatility for various applications.
Roxana Dinu   +3 more
wiley   +1 more source

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