Results 131 to 140 of about 106,036 (288)

Semaglutide and tirzepatide effects on cardiovascular outcomes in people with overweight or obesity in the real world (STEER)

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To assess the real‐world effectiveness of semaglutide versus tirzepatide in reducing major adverse cardiovascular events (MACE) among patients with overweight/obesity and established atherosclerotic cardiovascular disease (ASCVD) without diabetes in an insured US population.
Lauren Wilson, Zhenxiang Zhao, Victoria Divino, Matthew Bassan, Bríain Ó. Hartaigh, Signe Stensen, Kerem Ozer   +6 more
wiley   +1 more source

Renin, Angiotensin and Aldosterone in Relation to Electrolyte Metabolism [Abridged] [PDF]

, 1969
J. J. Brown, R. H. Chinn, G. Düsterdieck, R. Fräser, R H Gleadle, A.F. Lever, J. I. S. Robertson, M. Tree   +7 more
openalex   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

The adrenal gland and primary aldosteronism: anatomy, steroidogenesis, regulation, and genetic insights. [PDF]

Front Endocrinol (Lausanne)
Long KC, Azizan EA.
europepmc   +1 more source

Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma [PDF]

, 2017
Ute I. Scholl, Laura Abriola, Chengbiao Zhang, Esther N. Reimer, Mark S. Plummer, Barbara I. Kazmierczak, Junhui Zhang, Daniël Hoyer, Jane S. Merkel, Wen‐Hui Wang, Richard P. Lifton   +10 more
openalex   +1 more source

Risk of acute pancreatitis with DPP‐4 inhibitors versus SGLT2 inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki, Akira Okada, Yuya Kimura, Hideo Yasunaga   +3 more
wiley   +1 more source

Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats [PDF]

, 2008
Helmy M. Siragy, Chun Xue
openalex   +1 more source

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone, Erik Moedt, Hiddo J. L. Heerspink, Michael J. Davies, Manon Girard, David Z. I. Cherney, Marcel H. A. Muskiet   +6 more
wiley   +1 more source

Unmasking Early Cardiac Fibrosis in Sarcoidosis: The Role of Plasma Aldosterone and Cardiac MRI. [PDF]

J Clin Med
Giallafos E, Oikonomou E, Lama N, Katsanos S, Kolilekas L, Markozanes E, Pantoleon V, Zisimos K, Katsarou O, Theofilis P, Seitaridi G, Ilias I, Stratakos G, Kelekis N, Manali ED, Papiris S, Marinos G, Tsioufis K, Siasos G.   +18 more
europepmc   +1 more source

SAT-067 Insights into Paradoxical Bilateral Aldosterone Suppression in the Adrenal Veins of Patients with Primary Aldosteronism

, 2019
Taweesak Wannachalee, Aya T Nanba, James Shields, Richard J. Auchus, Adina F. Turcu   +4 more
openalex   +1 more source