Results 71 to 80 of about 2,710 (165)

Effects of Aliskiren on transdifferentiation induced by TGF-β₁ in human renal tubular epithelial cells

Linchuang shenzangbing zazhi, 2018
Objective To explore Aliskiren on transdifferentiation of renal tubular epithelial cells（ H KC） induced by TGF-β1 and to evaluate its effect on platelet derived growth factor（ PDGF-BB） 、vascular endothelialgrowth factor（ VEGF） expressing change. M ethods
HUANG Jian, CHEN Song, YANG Jing, MIN Ya-li   +3 more
doaj  

Renin inhibitors are a new direction in the treatment of arterial hypertension

Терапевтический архив, 2010
The paper covers current problems in the treatment of arterial hypertension. Renin is an important and promising therapeutic target. The direct renin inhibitor aliskiren (Rasilez) is a promising current effective antihypertensive agent that has cardio ...
Yuriy Aleksandrovich Vasyuk, Irina Akhmedkhanovna Sadulaeva, Elena Nikolaevna Yushchuk, Ol'ga Sergeevna Trofimenko, Mikhail Vasil'evich Chirkov, Viktoriya Sergeevna Fedoseeva, Kirill Georgievich Kulikov, Yu A Vasyuk, I A Sadulayeva, E N Yushchuk, O S Trofimenko, M V Chirkov, V S Fedoseyeva, K G Kulikov   +13 more
doaj  

Long-term effects of aliskiren on blood pressure and the renin-angiotensin-aldosterone system in hypertensive hemodialysis patients

International Journal of Nephrology and Renovascular Disease, 2012
Yoshiyuki Morishita1, Minami Watanabe1, Shiho Hanawa1, Osamu Iimura2, Sadao Tsunematsu3, Kenichi Ishibashi4, Eiji Kusano11Division of Nephrology, Department of Medicine, Jichi Medical University, Tochigi, Japan; 2Kumakura Clinic, Tochigi, Japan; 3Yuki ...
Morishita Y, Watanabe M, Hanawa S, Iimura O, Tsunematsu S, Ishibashi K, Kusano E   +6 more
doaj  

Acquired Angioedema-A Challenge in Medical Practice: A Narrative Review. [PDF]

J Clin Med
Poznańska-Kurowska K, Skibińska M, Lorenz D, Aman Ur Rahman W, Kurowski M.   +4 more
europepmc   +1 more source

Direct Renin Inhibition With Aliskiren Compared to Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Hypertension: A Systematic Review. [PDF]

Cureus
Gapizov A, Mohammad A, Singla S, Singla B, Kumawat S, Ajay, Ali Z.   +6 more
europepmc   +1 more source

Structure-Based Design and In Silico Evaluation of a Lipophilic Cyclooctanoyl- Derivative as a Renin Inhibitor: Lessons from Withdrawn Aliskiren. [PDF]

Int J Mol Sci
Pavlos D, Petsas E, Chatzipieris FP, Mavromoustakos T, Chasapis CT.   +4 more
europepmc   +1 more source

Effects of Inhibitors of the Activity of the Circulating Renin-Angiotensin System on the Growth and Proliferation of Endometrial Cancer Cells. [PDF]

Int J Mol Sci
Delforce SJ, Mohammed R, Symington TL, Wang Y, Verrills NM, Lumbers ER, Pringle KG.   +6 more
europepmc   +1 more source

Identification of novel dihydroorotate dehydrogenase (DHODH) inhibitors for cancer: computational drug repurposing strategy. [PDF]

BMC Pharmacol Toxicol
Rajamohamed R, Veerappapillai S.
europepmc   +1 more source

Comparative efficacy and safety of dual-combination vs. triple-combination antihypertensive therapies in hypertensive patients: an updated meta-analysis of randomized controlled trials. [PDF]

Front Pharmacol
Gong Z, Huang L, Long X, Zhang Y.
europepmc   +1 more source

Association between treatment-induced changes in the Kansas City Cardiomyopathy Questionnaire and clinical outcomes in chronic heart failure: a trial-level meta-regression analysis. [PDF]

Int J Cardiol Heart Vasc
Fukuta H, Goto T.
europepmc   +1 more source