Results 41 to 50 of about 229,471 (214)

ANet: Autoencoder-Based Local Field Potential Feature Extractor for Evaluating An Antidepressant Effect in Mice after Administering Kratom Leaf Extracts [PDF]

open access: yesarXiv, 2022
Kratom (KT) typically exerts antidepressant (AD) effects. However, evaluating which form of KT extracts possesses AD properties similar to the standard AD fluoxetine (flu) remained challenging. Here, we adopted an autoencoder (AE)-based anomaly detector called ANet to measure the similarity of mice's local field potential (LFP) features that responded ...
arxiv  

Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders

open access: yesInternational Journal on Biological Sciences, 2018
Neurodegenerative diseases are conventionally demarcated as disorders with selective loss of neurons. Conventional as well as newer molecules have been tested but they offer just symptomatic advantages along with abundant side effects.
G. Hussain   +8 more
semanticscholar   +1 more source

Rapid Quantification and Quantitation of Alkaloids in Xinjiang Fritillaria by Ultra Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry

open access: yesMolecules, 2017
The Fritillaria genus, including different kinds of medicinal and edible plants belonging to the Liliaceae family which have the function of treating and relieving a cough and eliminating phlegm, is widely planted in Xinjiang (China).
Aziz Mohammat   +2 more
doaj   +1 more source

Investigation of the effective components of the flowers of Trollius chinensis from the perspectives of intestinal bacterial transformation and intestinal absorption

open access: yesPharmaceutical Biology, 2017
Context: The flowers of Trollius chinensis Bunge (Ranunculaceae), used for respiratory tract infections, mainly contain flavonoids, phenolic acids, and alkaloids; however, the effective components are debatable because of their unclear in vivo activities.
Lina Guo   +7 more
doaj   +1 more source

Marine Alkaloids with Anti-Inflammatory Activity: Current Knowledge and Future Perspectives

open access: yesMarine Drugs, 2020
Alkaloids are nitrogenous compounds with various biological activities. Alkaloids with anti-inflammatory activity are commonly found in terrestrial plants, but there are few records of the identification and characterization of the activity of these ...
Cássio R M Souza   +2 more
semanticscholar   +1 more source

Ajmalicine Bioproduction in Catharanthus Roseus (L) G. Don Inoculated with Arbuscular Mycorrhiza and Fertilized with Nitrogen

open access: yesRevista Brasileira de Ciência do Solo, 2018
Catharanthus roseus (L) G. Don (Madagascar periwinkle) belongs to the Apocynaceace family and is widely spread throughout tropical and subtropical regions of the world.
Cecília Silva Monnerat   +6 more
doaj   +1 more source

Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety

open access: yesInternational Journal of Molecular Sciences, 2018
Pyrrolizidine alkaloids (PA) are widely distributed in plants throughout the world, frequently in species relevant for human consumption. Apart from the toxicity that these molecules can cause in humans and livestock, PA are also known for their wide ...
Rute Moreira   +3 more
semanticscholar   +1 more source

Natural Product Repertoire of the Genus Amphimedon

open access: yesMarine Drugs, 2018
Marine sponges are a very attractive and rich source in the production of novel bioactive compounds. The sponges exhibit a wide range of pharmacological activities. The genus Amphimedon consists of various species, such as viridis, compressa, complanata,
Nourhan Hisham Shady   +4 more
doaj   +1 more source

Isolation and identification of the alkaloids from rhizomes of Stephania macrantha

open access: yesGuangxi Zhiwu, 2023
To study the alkaloids in the rhizomes of Stephania macrantha. The total alkaloids of S. macrantha were extracted by acid extraction and alkali precipitation method. Eleven alkaloids have been isolated and purified by silica gel column chromatography and
Guofeng SUN   +4 more
doaj   +1 more source

Polycyclic Guanidine Alkaloids from Poecilosclerida Marine Sponges

open access: yesMarine Drugs, 2016
Sessile marine sponges provide an abundance of unique and diversified scaffolds. In particular, marine guanidine alkaloids display a very wide range of biological applications.
Estelle Sfecci   +3 more
doaj   +1 more source

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