Results 61 to 70 of about 483,373 (407)

The Occurrence and Bioactivities of Amaryllidaceae Alkaloids from Plants: A Taxonomy-Guided Genera-Wide Review

Plants
The distribution of Amaryllidaceae alkaloids, with a focus on their chemodiversity, has been reported previously, but not at a genera-wide diversity level.
G. David Lin, Pinky Vishwakarma, Paul N. Smith, Rachel W. Li   +3 more
doaj   +1 more source

Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review

Molecules, 2021
Pyrrolizidine alkaloids (PAs) are a widespread group of secondary metabolites in plants. PAs are notorious for their acute hepatotoxicity, genotoxicity and neurological damage to humans and animals.
Xianqin Wei, Weibin Ruan, Klaas Vrieling
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Cardiotropic medicinal products of plant origin. Prospects for use in modern clinical practice

Research Results in Pharmacology
Introduction: The aim of the research was to study the current state of use and improvement of the prospects for the using cardiological medicinal products obtained on the basis of medicinal plant raw materials.
Nadezhda V. Nesterova, Natalia D. Bunyatyan, Irina A. Samylina, Vladimir A. Evteev   +3 more
doaj   +1 more source

Foliar nitrogen supply enhances the recovery of photosynthetic performance of cold-stressed coffee (Coffea arabica L.) seedlings

Photosynthetica, 2020
Cold-stressed leaves possess an elevated risk of photodamage due to an inefficient photosynthetic apparatus during winter conditions. Recovery of cold-stressed coffee seedlings treated with different concentrations of nitrogen applied as foliar urea ...
R. ACIDRI, Y. SAWAI, Y. SUGIMOTO, D. SASAGAWA, T. MASUNAGA, S. YAMAMOTO, E. NISHIHARA   +6 more
doaj   +1 more source

Analysis of phytochemicals, minerals and in vitro antioxidant activities of Gongronema latifolium leaves [PDF]

, 2017
Gongronema latifolium is primarily used as spice and vegetable as well as a herb in traditional medicine in the treatment of malaria, diabetes and hypertension.
Chinwe, Igwe V., Usunomena, Usunobun
core   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

NMR Metabolomic Profiling of Differentiated SH-SY5Y Neuronal Cells: Amyloid-β Toxicity and Protective Effects of Galantamine and Lycorine

Cells
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by metabolic dysregulation, oxidative stress, amyloid-β (Aβ) aggregation, metal dyshomeostasis, and mitochondrial dysfunction.
Arian Kola, Filippo Costanti, Jordan Kahfi, Abdul-Hamid Emwas, Mariusz Jaremko, Daniela Valensin   +5 more
doaj   +1 more source

Variations of Alkaloid Accumulation and Gene Transcription in Nicotiana tabacum

Biomolecules, 2018
To increase the understanding of alkaloid biosynthesis in Nicotiana tabacum during whole plant growth periods, variations of the contents of alkaloids and the transcription of key biosynthetic genes in fresh leaves were investigated in three varieties at
Bo Sun, Yu-Xiao Tian, Fen Zhang, Qing Chen, Yong Zhang, Ya Luo, Xiao-Rong Wang, Fu-Cheng Lin, Jun Yang, Hao-Ru Tang   +9 more
doaj   +1 more source

Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective

Molecules, 2021
Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities.
Faisal Omar, Abu Montakim Tareq, Ali M. Alqahtani, Kuldeep Dhama, Mohammed Abu Sayeed, Talha Bin Emran, Jesus Simal-Gandara   +6 more
doaj   +1 more source