Results 1 to 10 of about 89,156 (285)
Ketone α-alkylation at the more-hindered site
Nature Communications, 2023 Control of the regioselectivity of α-alkylation of carbonyl compounds is a longstanding topic of research in organic chemistry. By using stoichiometric bulky strong bases and carefully adjusting the reaction conditions, selective alkylation of ...
Ming-Ming Li +6 more
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Versatile cell-based assay for measuring DNA alkylation damage and its repair
Scientific Reports, 2021 DNA alkylation damage induced by environmental carcinogens, chemotherapy drugs, or endogenous metabolites plays a central role in mutagenesis, carcinogenesis, and cancer therapy.
Yong Li +5 more
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Nature Communications, 2023 C−C bond forming reaction by alkylation of aryl rings is a main pillar of chemistry in the production of broad portfolios of chemical products. The dominant mechanism proceeds via electrophilic substitution of secondary and tertiary carbocations over ...
Xinze Du +3 more
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Alkylation of Dihydrofullerenes [PDF]
The Journal of Organic Chemistry, 2002 The fulleride dianions C(60)(2-) and C(70)(2-) were generated by deprotonation of the corresponding hydrogenated fullerenes, 1,2-C(60)H(2) and 1,2-C(70)H(2). These anions were prepared in the presence of a variety of alkylating agents, and mono- or dialkylated products were obtained. Alkylation was not successful with sulfonate ester alkylating agents.
Mark S. Meier +4 more
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Heterocyclic Communications, 2021 This mini-review encapsulates the latest findings (past 10 years) in the field of the deep eutectic solvents (DESs) application in the alkylation/arylation of different heterocyclic compounds.
Molnar Maja +4 more
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Copper(I)-catalyzed asymmetric alkylation of α-imino-esters
Nature Communications, 2023 Asymmetric alkylation of enolates is one of the most direct and important reactions to prepare α-chiral carbonyl compounds. Except for the classical methods that rely on the use of chiral auxiliaries, asymmetric catalysis emerged as a powerful tool ...
Zong-Ci Liu +3 more
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Meitan kexue jishu, 2023 Coal-tar pitch (CTP) is a substance produced by ambient and/or vacuum distillation of high-temperature coal tar, although CTP has a large yield in China, however its wide application is limited due to its high toxicity.
ZHANG Wenshuo +5 more
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Direct C2–H alkylation of indoles driven by the photochemical activity of halogen-bonded complexes
Beilstein Journal of Organic Chemistry, 2023 A light-driven metal-free protocol for the synthesis of sulfone-containing indoles under mild conditions is reported. Specifically, the process is driven by the photochemical activity of halogen-bonded complexes formed upon complexation of a sacrificial ...
Martina Mamone +4 more
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ChemInform Abstract: Alkyl—Alkyl Suzuki Cross‐Coupling of Unactivated Secondary Alkyl Chlorides. [PDF]
ChemInform, 2010 AbstractThe first alkyl—alkyl Suzuki reaction of unactivated secondary chlorides is applicable to both cyclic and acyclic secondary alkyl halides tolerating a variety of functional groups.
Lu, Zhe, Fu, Gregory C.
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ALKYLATION OF BENZENE WITH LONG CHAIN OLEFINS OVER SOLID-ACID CATALYST
Journal of Engineering, 2009 This investigation is concerned with the linear alkylbenzene production reaction by the alkylation of benzene with long chain olefins C10-C13 over various prepared solid acid catalysts.
Abdul Halim A. K. Mohammed +1 more
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