Results 101 to 110 of about 224,439 (406)
On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan. [PDF]
, 2016 A Friedel-Crafts alkylation is described that efficiently transforms tryptophan-containing peptides into macrocycles of varying ring connectivity. Factors are surveyed that influence the distribution of regioisomers, with a focus on indole C3-alkylations
Curtin, Brice H +5 more
core +1 more source
Advanced Synthesis &Catalysis, EarlyView.Abstract A strategy for the immobilization of Johnston's Mono(AMidine) catalyst (MAM) onto polystyrene, silica and hybrid silica‐polystyrene nanoparticles is presented. The catalyst activity was evaluated in the stereoselective aza‐Henry reaction leading to the pivotal β‐amino nitroalkane precursors of the anti‐cancer agents Nutlins (with Nutlin‐3a as ...
Sofia Toldo +8 more
wiley +1 more source
Copper-catalyzed arylation of alkyl halides with arylaluminum reagents
Beilstein Journal of Organic Chemistry, 2015 We report a Cu-catalyzed coupling between triarylaluminum reagents and alkyl halides to form arylalkanes. The reaction proceeds in the presence of N,N,N’,N’-tetramethyl-o-phenylenediamine (NN-1) as a ligand in combination with CuI as a catalyst.
Bijay Shrestha, Ramesh Giri
doaj +1 more source
Molecules, 2004 Synthesis of novel 5-methylidene-1,2,3,5-tetrahydro[2,1-b]-quinazolinederivatives 2-4 with potential biological activities mediated by α-adrenergic and/orimidazoline receptors was performed by reacting 2-chloro-4,5-dihydroimidazole (1) withthe ...
Maria Gdaniec +2 more
doaj +1 more source
Effect of ion structure on the physicochemical properties and gas absorption of surface active ionic liquids [PDF]
Physical Chemistry Chemical Physics, 2023, 25, 6808-6816Surface active ionic liquids (SAILs) combine useful characteristics of both ionic liquids (ILs) and surfactants, hence are promising candidates for a wide range of applications. However, the effect of SAIL ionic structures on their physicochemical properties remains unclear, which limits their uptake.
arxiv +1 more source
Structural, hydrogen bonding and dipolar properties of alkyl imidazolium-based ionic liquids: a classical and first-principles molecular dynamics study [PDF]
arXiv, 2022 Ionic liquids (ILs) feature a tailorable and wide range of structural, chemical and electronic properties that make this class of materials suitable to a broad variety of forefront applications in next-generation electronics. Yet, their intrinsic complexity call for special attention and experimental probes have still limitations in unraveling the ...
arxiv
Homoallylglycine residues are superior precursors to orthogonally modified thioether containing polypeptides. [PDF]
, 2018 Homoallylglycine N-carboxyanhydride, Hag NCA, monomers were synthesized and used to prepare polypeptides containing Hag segments with controllable lengths of up to 245 repeats.
Deming, Timothy J +2 more
core +1 more source
Manganese-Catalyzed α-Alkylation of Ketones, Esters, and Amides Using Alcohols
ACS Catalysis, 2018 Herein we report the manganese-catalyzed C–C bond-forming reactions via α-alkylation of ketones, amides, and esters, using primary alcohols. β-Alkylation of secondary alcohols by primary alcohols to obtain α-alkylated ketones is also reported.
S. Chakraborty +3 more
semanticscholar +1 more source
Continuous Flow Technology Enabling Photochemistry
Advanced Synthesis &Catalysis, Accepted Article.The merger of continuous flow technology and modern photochemistry has enabled countless applications showcasing new opportunities for chemical synthesis demonstrating improvements in selectivity, safety, sustainability and scalability. This focused review aims to highlight a selection of recently published case studies from academic and industrial ...
Ruairi Crawford, Marcus Baumann
wiley +1 more source
Photocatalytic Alkylation of C(sp3)−H Bonds Using Sulfonylhydrazones**
Angewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023 Herein, we report the realization of an alkyl‐alkyl cross‐coupling reaction, which combines N‐sulfonyl hydrazones and C(sp3)−H donors through a diarylketone‐enabled photocatalytic hydrogen atom transfer and a subsequent fragmentation of the obtained alkylated hydrazide.
Antonio Pulcinella +4 more
wiley +1 more source