Results 101 to 110 of about 196,000 (337)

Rhodium( i )-catalyzed cascade C(sp ² )–H bond alkylation – amidation of anilines: phosphorus as traceless directing group

, 2023
Marie Peng, Denis Ari, Thierry Roisnel, Henri Doucet, Jean‐François Soulé   +4 more
openalex   +2 more sources

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Synthesis of the fluorescent amino acid rac-(7-hydroxycoumarin-4-yl)ethylglycine

Beilstein Journal of Organic Chemistry, 2010
The hydrochloride of the racemic amino acid (7-hydroxycoumarin-4-yl)ethylglycine, a versatile fluorescent probe in proteins, has been synthesized in five steps from commercially available (7-hydroxycoumarin-4-yl)acetic acid.
Manfred Braun, Torsten Dittrich
doaj   +1 more source

Synthesis of functionalized polyisobutylene and its block copolymers with D,L-lactide

Журнал Белорусского государственного университета: Химия, 2019
Method of reactive polyisobutylene modification by various alkoxybenzenes (anisole and 4-phenoxybutanol) was proposed to form functionalized polyisobutylenes.
Pavel A. Nikishau, Evgenii A. Ksendzov, Dmitriy I. Shiman, Ludmila V. Gaponik, Sergei V. Kostjuk   +4 more
doaj   +1 more source

Flexible synthesis of polyfunctionalised 3-fluoropyrroles [PDF]

, 2016
An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes.
Cogswell, Thomas J., Donald, Craig S., Marquez, Rodolfo   +2 more
core   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Transmission Infrared Spectra of CH_3-, CD_3-, and C_(10)H_(21)-Ge(111) Surfaces [PDF]

, 2011
The surface chemistry of CH_3–, CD_3–, and C_(10)H_(21)–Ge(111) surfaces prepared through a bromination/alkylation method have been investigated by infrared spectroscopy. Well-ordered CH_3–Ge(111) surfaces could be prepared only if, prior to bromination,
Brunschwig, Bruce S., Knapp, David, Lewis, Nathan S.   +2 more
core   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source

Selective Conversion of Polyolefin Waste to Branched Alkanes via Methane‐Free Tandem Hydrocracking–Isomerization

Advanced Science, EarlyView.
Scheme illustrating the selective conversion of plastic waste to isomerized C4‐C12 products using RuSZ1 under different reaction conditions. ABSTRACT In recent years, catalytic hydrocracking has emerged as a promising waste‐to‐feedstock solution for processing plastic waste.
Xinbang Wu, Sitan Wang, Matilde Onofri, Kande Liu, Kun‐Han Lin, Roland C. Turnell‐Ritson, Li Shi, Xuan Meng, Paul J. Dyson   +8 more
wiley   +1 more source

Molecular modelling and Function Prediction of hABH7, human homologue of _E. coli_ ALKB7 [PDF]

, 2011
Human homologues of ALKB protein have shown the prime role in DNA damaging drugs, used for cancer therapy. Little is known about structure and function of hABH7, one of the members of this superfamily. Therefore, in the present study we intend to predict
Ambarish Sharan Vidyarthi, Mr. Shankaracharya, Saibal Das   +2 more
core   +1 more source