Results 191 to 200 of about 196,000 (337)

Late‐Stage Phenylation From [13C6] and [2H5]Benzene: A Versatile Tool for Stable Isotope Labeled MS Standards

Chemistry – A European Journal, EarlyView.
ABSTRACT We explored aryl thianthrenation as a tool for directly incorporating multiple isotopes into molecular scaffolds starting from full isotopically labeled benzene. Stable isotope‐labeled (SIL) molecules are indispensable tools for investigating chemical and biological mechanisms and quantifying metabolites.
Alexandre Labiche, Bouchaib Mouhsine, Dorian Dupommier, Louise Fogel, Frédéric Robert, David‐Alexandre Buisson, Frédéric Taran, Davide Audisio   +7 more
wiley   +1 more source

Photoredox/Nickel Dual-Catalyzed Asymmetric C-Alkylation of Nitroalkanes with α-Bromoketones. [PDF]

Org Lett
Rezazadeh S, Kim RS, Watson DA.
europepmc   +1 more source

2,4-Diamino-5-benzylpyrimidines and analogs as antibacterial agents. 2. C-Alkylation of pyrimidines with Mannich bases and application to the synthesis of trimethoprim and analogs

, 1980
Barbara Roth, Justina Z. Strelitz, Barbara S. Rauckman   +2 more
openalex   +1 more source

Rh‐Catalyzed [2 + 2 + 2] Cycloaddition of Linked Bis(Diynes) Ar‐C≡C‐C≡C‐(CH2)3‐C≡C‐C≡C‐Ar With Quinones: Synthesis and Photophysical Properties of Bis(Arylethynyl)‐Naphthoquinones and Anthraquinones

Chemistry – A European Journal, EarlyView.
We report the synthesis bis(arylethynyl)naphtho‐ and anthraquinones via Rh(I)‐catalyzed [2 + 2 + 2] cycloaddition reactions. The substrate scope of both quinones and linked bis‐diynes was explored. Microwave irradiation remarkably enhanced yields.
Luana A. Machado, Jianhua Han, Fábio G. Delolo, Joyce C. Oliveira, Breno U. Abreu, Hállen D. R. Calado, Joannes Krebs, Leibo Tan, Qing Ye, Tobias Groß, Christoph Lambert, Camille Latouche, Abdou Boucekkine, Jean‐François Halet, Holger Braunschweig, Todd B. Marder, Eufrânio N. da Silva Júnior   +16 more
wiley   +1 more source

Electrochemical C4 alkylation of pyridine derivatives: Enhanced regioselectivity via silane assistance. [PDF]

Sci Adv
Yang Z, Liu X, Chen YX, Gao Y, Xiao X, Maekawa H, Zhang T, Hao XQ, Song MP.   +8 more
europepmc   +1 more source

Ethylene oligomerization on bifunctional heterogeneous catalysts: model development and catalyst optimization [PDF]

, 2013
Marin, Guy, Thybaut, Joris, Toch, Kenneth   +2 more
core   +1 more source

Synthetic Studies towards Darobactin A

Chemistry – A European Journal, EarlyView.
The urgent need for new antibiotics led us to develop a new methodology for the synthesis of the natural product darobactin A selectively targeting gram‐negative bacteria. This study provides new insights into the synthesis of strained indole‐containing macrocycles.
Till Steiner, Antoine Versini, Marco Schellenberg, Emma Schuler, Karl Gademann   +4 more
wiley   +1 more source

Enantioselective copper-catalysed defluorinative alkylation of polyfluoroarenes with alkenes and 1,3-dienes. [PDF]

Chem Sci
Shi D, Zhu L, Jiang Y, Wang S, Yin J, Yuan X, Ma S, Li X, Sun J, Zhang Q, Xiong T.   +10 more
europepmc   +1 more source

Supplementary Dataset 1 from Alkylation Sensitivity Screens Reveal a Conserved Cross-species Functionome

, 2023
David Svilar, Madhu Dyavaiah, Ashley R. Brown, Jiang-bo Tang, Jianfeng Li, Peter R. McDonald, Tong Ying Shun, Andrea Braganza, Xiaohong Wang, Salony Maniar, Claudette M. St. Croix, John S. Lazo, Ian F. Pollack, Thomas J. Begley, Robert W. Sobol   +14 more
openalex   +1 more source

Fluorescence Properties and Mg2+ Selectivity of Aryl‐Alkynyl Derivatives of the o‐Aminophenoltriacetate (APTRA) Ligand

Chemistry – A European Journal, EarlyView.
It is a challenge to improve the selectivity of high‐denticity ligands for Mg2+ over Ca2+. We show that in aryl‐alkynyl derivatives of APTRA, electron‐withdrawing substituents lower the binding affinity for Ca2+ more than Mg2+, making the ligand more selective for Mg2+.
Laura L. Duncan, Christopher Hogg, J. A. Gareth Williams   +2 more
wiley   +1 more source