Results 151 to 160 of about 66,858 (295)

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

open access: yesAngewandte Chemie, EarlyView.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou   +7 more
wiley   +2 more sources

Ultrastable Self‐Cross‐linkable Electro‐Optic Materials Based on a Bisanthracene Scaffold

open access: yesAdvanced Electronic Materials, EarlyView.
A novel bisanthracene‐based self‐cross‐linkable electro‐optic chromophore (TD2) is developed. TD2 exhibits a high r33 of 141 pm/V and a cross‐linked Tg up to 195 °C, retaining 99.75% of its initial EO response after 500 h at 85 °C, showing record‐high thermal stability for single‐molecule self‐cross‐linking EO materials.
Xingtao Wang   +6 more
wiley   +1 more source

Fabrication of Composite Cathode for All‐Solid‐State Sodium Batteries

open access: yesAdvanced Energy Materials, EarlyView.
The design of composite cathodes for all‐solid‐state sodium batteries must address three critical challenges—interfacial side reactions, interfacial delamination, and highly tortuous transport pathways. This work outlines structural and interfacial strategies to optimize ion transport and mechanical stability, enabling durable, and high‐performance ...
Gaoming Sun   +6 more
wiley   +1 more source

Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant

open access: yesAngewandte Chemie, EarlyView.
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey   +13 more
wiley   +1 more source

Direct Access to Chiral Piperidines by Enantioselective HAT‐Initiated C(sp3)─H Oxidation

open access: yesAngewandte Chemie, EarlyView.
The direct desymmetrization of piperidines is achieved through manganese‐catalyzed enantioselective α‐C(sp3)─H oxidation with hydrogen peroxide, affording versatile chiral N,O‐acetals in good yields and with high enantio‐ and diastereoselectivity. These intermediates provide access to diverse functionalized piperidines with retention of chirality ...
Sethuraman Muthuramalingam   +5 more
wiley   +1 more source

Metabolic Labeling and Visualization of Isoprenoids Using Alkyne-Modified DMAPP Analogs in Bacillus subtilis. [PDF]

open access: yesAngew Chem Int Ed Engl
Hulsey ZN   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy