Results 151 to 160 of about 36,889 (205)

Metal-Free Electrophilic Borylative Cyclizations of Alkynes. [PDF]

open access: yesChem Rec
Mateos-Gil J   +3 more
europepmc   +1 more source

Computer Vision Enables Monitoring and Kinetic Analysis of Structurally Diverse Carbon Monoxide Surrogates

open access: yesAngewandte Chemie, EarlyView.
A non‐contact computer vision method enables monitoring and quantitative comparison of vessel‐specific CO release kinetics from structurally diverse surrogates in two‐chamber COware reactors, revealing that surrogate reactivity scores correlate with carbonylation reaction outcomes.
Kristin Donnachie   +4 more
wiley   +1 more source

Recent Advances in Nickel Catalysts for Sonogashira Coupling. [PDF]

open access: yesChemistryOpen
Payamifar S   +2 more
europepmc   +1 more source

Dual Activation of H2 and CO2 by a Pincer‐Type Ni–Zn Heterobimetallic Complex

open access: yesAngewandte Chemie, EarlyView.
A bimetallic Ni−Zn complex performs sequential activations of H2 (1 equiv) and CO2 (2 equiv). This bimetallic cooperativity is attributed to the weak Lewis acidic nature of Zn(II), which promotes fluxional ligand binding. Namely, an X‐type ligand at Ni, where X is hydride or formate, toggles between two different binding modes: bridging Zn(μ‐X)Ni and ...
Krishnendu Dey   +3 more
wiley   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

open access: yesAngewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv   +9 more
wiley   +1 more source

RNA-binding landscape of amiloride: large-scale profiling and structural basis of U-U mismatch recognition. [PDF]

open access: yesRSC Chem Biol
Tsuzuki K   +8 more
europepmc   +1 more source

Three Component Thio‐ and Carboboration of Alkynes: A Modular Route to Functionalised Bicyclic Boronates

open access: yesAngewandte Chemie, EarlyView.
Three‐component thio‐ and carbo‐boration reactions to form functionalised benzoxaborinines and benzazaborinines are reported. The nucleophile scope includes thioethers, thiols, and (hetero)arenes. Mechanistic studies revealed a disparity between thioboration using thioethers and using thiols.
Laura Winfrey   +4 more
wiley   +1 more source

Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery

open access: yesAngewandte Chemie, EarlyView.
We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne   +5 more
wiley   +1 more source

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