Results 11 to 20 of about 50,798 (264)
Effect of Ozone on Allergic Airway Inflammation [PDF]
ABSTRACT Background Exposure to O 3 has been associated with increased risk of exacerbations of asthma, but the underlying mechanisms are not well studied.
Mehrdad Arjomandi +4 more
openaire +4 more sources
Pathogenesis of Allergic Airway Inflammation [PDF]
Advances have been made in defining the mechanisms for the control of allergic airway inflammation in response to inhaled antigens. Several genes, including ADAM33, DPP10, PHF11, GPRA, TIM-1, PDE4D, OPN3, and ORMDL3, have been implicated in the pathogenesis and susceptibility to atopy and asthma.
Devendra K, Agrawal, Zhifei, Shao
openaire +2 more sources
Daily inhaled antigens induce cellular immune response in the airways. In case of allergens, allergic airway inflammation is usually represented by eosinophils, however, neutrophil infiltration is also observed during severe asthma.
M. A. Shevchenko +2 more
doaj +1 more source
Airway Fibrinogenolysis and the Initiation of Allergic Inflammation [PDF]
Abstract The past 15 years of allergic disease research have produced extraordinary improvements in our understanding of the pathogenesis of airway allergic diseases such as asthma. Whereas it was previously viewed as largely an immunoglobulin E-mediated process, the gradual recognition that T cells, especially Type 2 T helper (Th2 ...
Valentine Ongeri, Millien +7 more
openaire +2 more sources
The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma
Background The interleukin 17 receptor E (IL-17RE) is specific for the epithelial cytokine interleukin-17C (IL-17C). Asthma exacerbations are frequently caused by viral infections.
Giovanna Vella +7 more
doaj +1 more source
Allergic airway inflammation is one of the primary features of allergic asthma. Interleukin-33 (IL-33) is recognized as a key pro-inflammatory cytokine that mediates allergic airway inflammation, and its expression is elevated in this condition, but ...
Yusuke Yamazumi +15 more
doaj +1 more source
Surfactant and allergic airway inflammation
Pulmonary surfactant is a complex mixture of unique proteins and lipids that covers the airway lumen. Surfactant prevents alveolar collapse and maintains airway patency by reducing surface tension at the air-liquid interface. Furthermore, it provides a defence against antigen uptake by binding foreign particles and enhancing cellular immune responses ...
Carla Winkler, Jens Michael Hohlfeld
openaire +3 more sources
Role of Cytokines in Allergic Airway Inflammation [PDF]
Asthma is characterized by intense infiltration of eosinophils and CD4+ T cells into the submucosal tissue of airways. Accumulating evidence indicates that T helper type 2 cell-derived cytokines such as interleukin (IL)-4, IL-5 and IL-13 play critical roles in orchestrating and amplifying allergic inflammation in asthma.
Hiroshi, Nakajima, Kiyoshi, Takatsu
openaire +2 more sources
Interleukin-10 multitasking in allergic airway inflammation. [PDF]
Hendriks RW.
europepmc +4 more sources
Background Allergic asthma is a common respiratory disease that significantly impacts human health. Through in silico analysis of human lung RNASeq, we found that asthmatic lungs display lower levels of Isthmin-1 (ISM1) expression than healthy lungs ...
Jong Huat Tee +7 more
doaj +1 more source

