Results 31 to 40 of about 936,865 (297)

The effect of macrolides on allergic rhinitis versus chronic rhinosinusitis- an in-vitro study [PDF]

, 2009
PhDBackground The mechanisms of the rhinitic process are complex. Previous studies upon nasal epithelial cells have begun to investigate rhinitis.
Kuchai, Romana
core   +4 more sources

Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation [PDF]

, 2015
SummaryLung nociceptors initiate cough and bronchoconstriction. To elucidate if these fibers also contribute to allergic airway inflammation, we stimulated lung nociceptors with capsaicin and observed increased neuropeptide release and immune cell ...
Bruce D. Levy, Laedermann, Cedric, Agac, Busranour, Bruce P. Bean, Matthew DiBiase, Foster, S., Nader Ghasemlou, Foster, Simmie L., Simmie L. Foster, Oliver Haworth, Cronin, S., Maud A. Pascal, Von Hehn, C., Pascal, Maud A., Haworth, O., Levy, Bruce D., Pascal, M., Talbot, S., Woolf, Clifford J., Hiroyuki Seki, Clifford J. Woolf, Haworth, Oliver, Abdulnour, Raja-Elie E., Seki, Hiroyuki, Kuchroo, V., Roberson, David, Christian Von Hehn, Cronin, Shane J.F., Isaac M. Chiu, Lai, N., Patrick R. Burkett, Penninger, J., Ghasemlou, N., Von Hehn, Christian, Burkett, Patrick R., Chiu, I., Bean, Bruce P., Shane J.F. Cronin, Woolf, C., Lee, Seungkyu, Seungkyu Lee, Busranour Agac, Lee, S., Sébastien Talbot, Nicole Lai, Agac, B., Josef M. Penninger, Kuchroo, Vijay K., Burkett, P., Tran, Johnathan V., Ghasemlou, Nader, Raja-Elie E. Abdulnour, DiBiase, Matthew, DiBiase, M., Vijay K. Kuchroo, Seki, H., Laedermann, C., Johnathan V. Tran, Chiu, Isaac M., Abdulnour, R., Tran, J., Roberson, D., Levy, B., Talbot, Sébastien, Bean, B., David Roberson, Lai, Nicole, Penninger, Josef M., Cedric Laedermann   +68 more
core   +1 more source

Ambient ozone, and urban PM2.5 co-exposure, aggravate allergic asthma via transient receptor potential vanilloid 1-mediated neurogenic inflammation

Ecotoxicology and Environmental Safety, 2022
Allergic asthma is the most common pulmonary inflammatory disease, and epidemiological studies have revealed that PM2.5 or ambient ozone (O3) exposure contribute to the higher prevalence of allergic asthma. Current experimental evidence focus principally
Zongpei Lian, Haomin Qi, Xudong Liu, Yuchao Zhang, Ruijia Xu, Xu Yang, Yan Zeng, Jinquan Li   +7 more
doaj   +1 more source

Nox enzymes in allergic airway inflammation [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011
Chronic airway diseases such as asthma are linked to oxidative environmental factors and are associated with increased production of reactive oxygen species (ROS). Therefore, it is commonly assumed that oxidative stress is an important contributing factor to asthma disease pathogenesis and that antioxidant strategies may be useful in the treatment of ...
openaire   +2 more sources

Neural regulation of ILC2s in allergic airway inflammation

Frontiers in Allergy, 2023
The sympathetic nervous system (SNS) and parasympathetic nervous system (PNS) regulate the effector functions of group 2 innate lymphoid cells (ILC2s) through β2 adrenergic receptor (ADRB2) and nicotinic/muscarinic cholinergic receptor signaling, respectively.
Christopher M. Thomas, R. Stokes Peebles, R. Stokes Peebles, R. Stokes Peebles   +3 more
openaire   +3 more sources

Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling [PDF]

, 2005
Background: Sub- epithelial extracellular matrix deposition is a feature of asthmatic airway remodelling associated with severity of disease, decline in lung function and airway hyperresponsiveness.
Reinhardt Alistair K, Robin J McAnulty, Reinhardt, AK, McAnulty Robin J, Geoffrey J Laurent, Laurent, GJ, Laurent Geoffrey J, Bottoms, SE, Bottoms Stephen E, McAnulty, RJ, Stephen E Bottoms, Alistair K Reinhardt   +11 more
core   +2 more sources

Chemokine CXCL12 drives pericyte accumulation and airway remodeling in allergic airway disease

Respiratory Research, 2022
Background Airway remodeling is a significant contributor to impaired lung function in chronic allergic airway disease. Currently, no therapy exists that is capable of targeting these structural changes and the consequent loss of function. In the context
Rebecca Bignold, Bushra Shammout, Jessica E. Rowley, Mariaelena Repici, John Simms, Jill R. Johnson   +5 more
doaj   +1 more source

Mediators and Cytokines in Persistent Allergic Rhinitis and Nonallergic Rhinitis with Eosinophilia Syndrome [PDF]

, 2012
Background: Patients with nonallergic rhinitis with eosinophilia syndrome (NARES) show typical symptoms of persistent allergic rhinitis (PAR). The aim of the present study was to compare nasal cytokine patterns between NARES and PAR.
Canis, Martin, Wendt, Sebastian, Gröger, Moritz, Klemens, Christine, Groeger, Moritz, Kramer, Matthias F., Becker, Sven, Havel, Miriam, Pfrogner, Elisabeth, Rasp, Gerd   +9 more
core   +1 more source

Roles of IL-22 in Allergic Airway Inflammation [PDF]

Journal of Allergy, 2013
IL-23- and IL-17A-producing CD4+ T cell (Th17 cell) axis plays a crucial role in the development of chronic inflammatory diseases. In addition, it has been demonstrated that Th17 cells and their cytokines such as IL-17A and IL-17F are involved in the pathogenesis of severe asthma. Recently, IL-22, an IL-10 family cytokine that is produced by Th17 cells,
Koichi Hirose, Kentaro Takahashi, Hiroshi Nakajima   +2 more
openaire   +2 more sources

Omalizumab: clinical use for the management of asthma [PDF]

, 2012
Omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, is a treatment option for patients with moderate to severe allergic asthma whose asthma is poorly controlled with inhaled corticosteroids and inhaled long-acting ß2 agonist ...
Rekha Chaudhuri, Neil C. Thomson, Thomson, N.C., Chaudhuri, R.   +3 more
core   +1 more source