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Therapeutic implications of allopregnanolone in Alzheimer’s related depression
Behavioural Brain ResearchAlzheimer's disease (AD) and depression share common neuropathological mechanisms, with neuroinflammation, mitochondrial dysfunction, and impaired neurosteroid signalling contributing to both conditions. Allopregnanolone (ALLO), a potent neurosteroid, plays a crucial role in modulating mood, cognition, and neuroprotection via its interaction with GABA ...
Balaji, Tidke +6 more
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ALCOHOL AND ALLOPREGNANOLONE LEVELS.
Alcoholism: Clinical & Experimental Research, 2004S Nyberg +5 more
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The allopregnanolone to progesterone ratio across the menstrual cycle and in menopause
Psychoneuroendocrinology, 2020Maren B Nyer +2 more
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Pharmacokinetic and behavioral effects of allopregnanolone in healthy women
Psychopharmacology, 2005Sigrid Nyberg +2 more
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Tolerance to allopregnanolone with focus on the GABA‐A receptor
British Journal of Pharmacology, 2011Sahruh Turkmen +2 more
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The Neurosteroid Allopregnanolone Is Reduced in Prefrontal Cortex in Alzheimer’s Disease
Biological Psychiatry, 2006Christine E Marx +2 more
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