Results 41 to 50 of about 2,738 (186)

Pathways of major histocompatibility complex allorecognition [PDF]

open access: yesCurrent Opinion in Organ Transplantation, 2008
Here, we review the pathways of allorecognition and their potential relevance to the balance between regulatory and effector responses following transplantation.Transplantation between nonidentical members of the same species elicits an immune response that manifests as graft rejection or persistence.
Afzali, Ben   +2 more
openaire   +5 more sources

Phylogenomics and systematics of botryllid ascidians, and implications for the evolution of allorecognition

open access: yesFrontiers in Ecology and Evolution, 2023
Allorecognition, the ability of an organism to distinguish kin from non-kin, or self from non-self, has been studied extensively in a group of invertebrate chordates, the colonial ascidians called botryllids (Subphylum Tunicata, Class Ascidiacea, Family ...
Marie L. Nydam   +9 more
doaj   +1 more source

The ‘immunology trap’ of anthozoans [PDF]

open access: yesInvertebrate Survival Journal, 2011
Organisms commonly respond to infectious agents via effector arms of immune systems. However, whereas innate immunity in vertebrates has been intensely investigated, we still strive to understand how cnidarians’ immunity operates, consulting literature ...
B Rinkevich
doaj   +1 more source

Mathematical modeling of early cellular innate and adaptive immune responses to ischemia/reperfusion injury and solid organ allotransplantation

open access: yesFrontiers in Immunology, 2015
A mathematical model of the early inflammatory response in transplantation is formulated with ordinary differential equations. We first consider the inflammatory events associated only with the initial surgical procedure and the subsequent ischemia ...
Judy D Day   +3 more
doaj   +1 more source

Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition

open access: yesJournal of Immunology Research, 2016
In organ transplantation, alloantigens are taken up by antigen presenting cells and presented via the indirect pathway to T-cells which in turn can induce allograft rejection.
Eytan Breman   +6 more
doaj   +1 more source

PATHWAYS OF RECOGNITION OF FOREIGN ANTIGENS IN THE ADAPTIVE IMMUNE RESPONSE TO ALLOGENEIC ORGAN TRANSPLANTATION

open access: yesВестник трансплантологии и искусственных органов, 2016
Immunological allograft rejection is based on the process of recognition of donor antigens by T-cell receptors. Antigens are generally represented by molecules of major hystocompatibility complex (MHC), expressed by the donor organ tissue cells.
A. S. Berkos, G. V. Nikolaev
doaj   +1 more source

Colony specificity in Botrylloides leachi. I. Morphological aspects [PDF]

open access: yesInvertebrate Survival Journal, 2006
We studied colony specificity in the colonial ascidian Botrylloides leachi which, as in other botryllid ascidians, leads to either fusion or non-fusion between contacting colonies.
G Zaniolo, L Manni, L Ballarin
doaj   +1 more source

Botryllus schlosseri allorecognition: tackling the enigma [PDF]

open access: yesDevelopmental & Comparative Immunology, 2015
Allorecognition has been well-studied in the context of vertebrate adaptive immunity and recognition of the Major Histocompatibility Complex (MHC), which is the central event of vertebrate immune responses. Although allorecognition systems have been identified throughout the metazoa, recent results have shown that there is no apparent conservation or ...
Taketa, Daryl A, De Tomaso, Anthony W
openaire   +4 more sources

Synergies of Extracellular Vesicles and Microchimerism in Promoting Immunotolerance During Pregnancy

open access: yesFrontiers in Immunology, 2022
The concept of biological identity has been traditionally a central issue in immunology. The assumption that entities foreign to a specific organism should be rejected by its immune system, while self-entities do not trigger an immune response is ...
José M. Murrieta-Coxca   +4 more
doaj   +1 more source

Patterns of 1,748 Unique Human Alloimmune Responses Seen by Simple Machine Learning Algorithms

open access: yesFrontiers in Immunology, 2020
Allele specific antibody response against the polymorphic system of HLA is the allogeneic response marker determining the immunological risk for graft acceptance before and after organ transplantation and therefore routinely studied during the patient's ...
Angeliki G. Vittoraki   +12 more
doaj   +1 more source

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