Results 61 to 70 of about 48,611 (207)

Synthesis of 2-(2-R1-Hydrazino)-5-(R2-benzyl)-2-thiazolines on the Basis of Meerweins Arylation Products of Allyl Isothiocyanate

Molecules, 2003
3-Aryl-2-chloropropylisothiocyanates (1) are formed by interaction of arenediazonium chlorides with allyl isothiocyanate. Adducts 1 react with monoacylhydrazines to form 1-acyl-4-(3-aryl-2-chloropropyl)thiosemicarbazides (2a–d).
Mykola I. Ganushchak, Mykola D. Obushak, Volodymyr V. Karpyak   +2 more
doaj   +1 more source

Enantiomerically Enriched Tetrahydropyridine Allyl Chlorides [PDF]

, 2019
Enantiomerically enriched allyl halides are rare due to their configurational lability. Here we report stable piperidine-based allyl chloride enantiomers.
Robert, Paton, Alexandre, Brethomé, Stephen P., Fletcher, Thomas, Palacin, Sedef, Karabiyikoglu   +4 more
core   +2 more sources

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

The Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Soil Disinfestation Efficacy against Soil Fungal Pathogens in Strawberry Crops in Spain: An Overview

Agronomy, 2021
(1) Background: Strawberry cultivation is highly dependent on soil disinfestation for proper development. Since the definitive methyl bromide phase-out, other chemicals have been used as alternatives.
Berta de los Santos, Juan Jesús Medina, Luis Miranda, José Antonio Gómez, Miguel Talavera   +4 more
doaj   +1 more source

Isothiocyanates in medicine: A comprehensive review on phenylethyl-, allyl-, and benzyl-isothiocyanates

Pharmacological Research
In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects. This comprehensive review provides an in-depth exploration of the therapeutic potential and individual biological mechanisms of ...
Cosima C. Hoch, Maria Shoykhet, Tobias Weiser, Lena Griesbaum, Julie Petry, Khouloud Hachani, Gabriele Multhoff, Ali Bashiri Dezfouli, Barbara Wollenberg   +8 more
openaire   +3 more sources

Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera

eFood, Volume 7, Issue 5, October 2026.
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana, Julia da Costa Santos, Ana Caroline de Medeiros Dantas, David Henrique Xavier Barbosa, Matheus de Freitas Fernandes Pedrosa, Pablo Felipe Ferreira Farias, Susana Margarida Gomes Moreira, Patrícia Prado Augusto, Patricia Santos Lopes, Ana Paula Barreto Gomes, Rui de Oliveira Macedo, Francisco Canindé de Sousa Júnior, Cristiane Fernandes de Assis   +12 more
wiley   +1 more source

Behavioral Aversion to AITC Requires Both Painless and dTRPA1 in Drosophila

Frontiers in Neural Circuits, 2018
There has been disagreement over the functional roles of the painless gene product in the detection and subsequent behavioral aversion to the active ingredient in wasabi, allyl isothiocyanate (AITC).
Samantha J. Mandel, Madison L. Shoaf, Jason T. Braco, Wayne L. Silver, Wayne L. Silver, Erik C. Johnson, Erik C. Johnson   +6 more
doaj   +1 more source

Scientific Opinion on the safety and efficacy of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups (chemical group 20) when used as flavourings for all animal species [PDF]

EFSA Journal, 2013
Chemical group 20 consists of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups, of which 31 are currently authorised for use as flavours in food.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Can trigeminal sensations impact saltiness perception? A mini‐review

Journal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 7540-7546, October 2026.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan, Nicoletta Faraone, Matthew B McSweeney   +2 more
wiley   +1 more source