Results 181 to 190 of about 5,366 (218)

Remote Loading of Aloe Emodin in Gemini-Based Cationic Liposomes

Langmuir, 2014
Anthraquinone compound aloe-emodin (AE) has shown antineoplastic, antibacterial, antiviral, and anti-inflammatory properties and scavenging activity on free radicals. Because of these therapeutic features, AE has been attracting increasing interest and could be applied in the curing of many diseases.
Chiara Giuliani, Barbara Altieri, Cecilia Bombelli, GALANTINI, Luciano, Giovanna Mancini, Annarita Stringaro   +5 more
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Aloe emodin inhibits the cytotoxic action of tumor necrosis factor

European Journal of Pharmacology, 2007
We demonstrate the capacity of an herbal anthraquinone aloe emodin to reduce the cytotoxicity of the proinflammatory cytokine tumor necrosis factor (TNF) towards L929 mouse fibrosarcoma and U251 human glioma cell lines. Aloe emodin inhibited both TNF-induced cell necrosis and apoptosis, but it did not reduce cell death induced by UV radiation or ...
Harhaji-Trajković, Ljubica, Mijatović, Sanja, Maksimović-Ivanić, Danijela, Popadić, Dusan, Isaković, Aleksandra, Todorović-Marković, Biljana, Trajković, Vladimir   +6 more
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Aloe emodin decreases the ERK-dependent anticancer activity of cisplatin

Cellular and Molecular Life Sciences, 2005
The present study describes the ability of an anthraquinone derivative aloe emodin (AE) to reduce the cytotoxic activity of the platinum(II)-based anticancer agent cisplatin toward murine L929 fibrosarcoma and C6 glioma cell lines. The protective effect of AE was demonstrated by MTT and crystal violet assays for cell viability, and involved supression ...
Mijatović, Sanja, Maksimović-Ivanić, Danijela, Radović, Julijana, Miljković, Đorđe, Kaluđerović, Goran N., Sabo, Tibor J, Trajković, Vladimir   +6 more
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Rhein and Aloe-Emodin Kinetics from Senna Laxatives in Man

Pharmacology, 1993
Therapeutic doses of two laxatives (Agiolax and Sennatin) were repeatedly administered to 10 healthy volunteers in a two-way change-over design. Blood samples were collected up to 96 h after the first dose, and plasma levels of total aloe-emodin and rhein were determined simultaneously with a sensitive (lower limit of quantification: 0.5 ng aloe-emodin
G, Krumbiegel, H U, Schulz
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Cell-type dependent response of melanoma cells to aloe emodin

Food and Chemical Toxicology, 2012
Intrinsic characteristics of melanoma cells such as expression of inducible nitric oxide synthase (iNOS), redox status, and activity of signaling pathways involved in proliferation, differentiation and cell death define the response of the cells to the diverse treatments.
Radović, Julijana M, Maksimović-Ivanić, Danijela, Timotijević, Gordana S, Popadić, S, Ramić, Zorica D., Trajković, Vladimir S, Miljković, Đorđe, Stošić-Grujičić, Stanislava, Mijatović, Sanja   +8 more
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Synthesis and Antitumor Activity of Natural Compound Aloe Emodin Derivatives

Chemical Biology & Drug Design, 2014
In this study, we have synthesized novel water soluble derivatives of natural compound aloe emodin 4(a–j) by coupling with various amino acid esters and substituted aromatic amines, in an attempt to improve the anticancer activity and to explore the structure–activity relationships.
Naraganahalli R, Thimmegowda, Chanmi, Park, Bettaswamigowda, Shwetha, Krisada, Sakchaisri, Kangdong, Liu, Joonsung, Hwang, Sangku, Lee, Sook J, Jeong, Nak K, Soung, Jae H, Jang, In-Ja, Ryoo, Jong S, Ahn, Raymond L, Erikson, Bo Y, Kim   +13 more
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Aloe‐emodin: A review of its pharmacology, toxicity, and pharmacokinetics

Phytotherapy Research, 2019
Aloe‐emodin is a naturally anthraquinone derivative and an active ingredient of Chinese herbs, such as Cassia occidentalis, Rheum palmatum L., Aloe vera, and Polygonum multiflorum Thunb. Emerging evidence suggests that aloe‐emodin exhibits many pharmacological effects, including anticancer, antivirus, anti‐inflammatory, antibacterial, antiparasitic ...
Xiaoxv Dong, Yawen Zeng, Yi Liu, Longtai You, Xingbin Yin, Jing Fu, Jian Ni   +6 more
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Metabolic Activation and Cytotoxicity of Aloe-Emodin Mediated by Sulfotransferases

Chemical Research in Toxicology, 2019
Aloe-emodin (AE) is a major anthraquinone ingredient of numerous traditional Chinese medicines with a variety of beneficial biological activities in vitro. Previous studies suggested that AE possessed cytotoxicity and genotoxicity. Nevertheless, the mechanisms of the toxic action of AE have not yet been fully clarified.
Ruihong Li, Wei Li, Yutong You, Xiucai Guo, Ying Peng, Jiang Zheng   +5 more
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Photodynamic Inactivation of Staphylococcus aureus Using Aloe-emodin as Photosensitizer

Food Research International
Aloe-emodin (AE) is a natural compound with photodynamic properties. The aim of this study was to investigate the inhibitory effect of AE-mediated photodynamic inactivation (PDI) on Staphylococcus aureus (S. aureus). The bacteriostatic efficiency under different photodynamic conditions and photosensitizing mechanism was studied in detail.
Jiali Wu, Yaokun Pang, Dan Liu, Jianxia Sun, Weibin Bai   +4 more
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Facile Synthesis of the (±)‐6‐Deoxycarminomycinone from Aloe‐Emodin

Angewandte Chemie International Edition in English, 1983
AbstractThe complete manuscript of this communication appears in: Angew. Chem. Suppl. 1983, 1267.
Karsten Krohn, Burkhard Sarstedt
openaire   +1 more source