Results 121 to 130 of about 26,643 (286)

Effects of Alpha Lipoic Acid Supplementation on Slow Skeletal Muscle Mass and Contractile Functions in Type 2 Diabetic Male Sprague Dawley Rats

open access: yesLife and Science
Objective: To see the Effects of Alpha-Lipoic Acid (ALA) supplementation on slow skeletal muscle mass and contractile functions in type 2 diabetic male Sprague Dawley rats. Study Design: Quasi-experimental study.
Barkat Ullah Khan   +5 more
doaj   +1 more source

Vascular Dysfunction and Posttraumatic Stress Disorder: Examining the Role of Oxidative Stress and Sympathetic Activity [PDF]

open access: yes, 2020
Purpose: The physiological manifestations of posttraumatic stress disorder (PTSD) have been associated with an increase in risk of cardiovascular disease (CVD) independent of negative lifestyle factors.
Autler, Aaron   +6 more
core   +1 more source

Screening of isoquinoline alkaloids for potent lipid metabolism modulation with Caenorhabditis elegans. [PDF]

open access: yes, 2013
Metabolic syndrome and related disorders are increasingly prevalent in contemporary society, and thus pose the need for potent agents to control lipid accumulation in the body.
Chow, Yit-Lai, Sato, Fumihiko
core   +1 more source

Dynamic Gelatin Hydrogels Crosslinked by Dithiolane‐Norbornene Click Chemistry

open access: yesMacromolecular Bioscience, Volume 26, Issue 2, February 2026.
Gelatin‐norbornene (GelNB) and poly(ethylene glycol)‐tetra‐lipoic acid (PEG4LA) are modularly photo‐crosslinked into gelatin‐based hydrogels with dynamically tunable mechanics for expansion and differentiation of induced pluripotent stem cells (iPSC). ABSTRACT Hydrogels prepared from gelatin are ideal for mimicking the extracellular matrix (ECM) owing ...
Favour O. Afolabi   +2 more
wiley   +1 more source

Neuroprotective effects of α-lipoic acid on the development of oxidative stress and astrogliosis in the brain of STZ-diabetic rats

open access: yesRegulatory Mechanisms in Biosystems, 2014
The aim of this study was to examine whether the antioxidant alpha-lipoic acid protects neurons from diabetic-reperfusion injury. The streptozotocin (STZ) rat model was used to study the glial reactivity and prevention of gliosis by alpha-lipoic acid ...
S. Kyrychenko   +4 more
doaj   +1 more source

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin   +10 more
wiley   +1 more source

An Oral Antioxidant Formulation Delaying and Potentially Reversing [PDF]

open access: yes, 2015
This is the final published version. It first appeared at http://clinmedlibrary.com/articles/ijdcr/ijdcr-2-023.php?jid=ijdcr.Background: The majority of dogs with diabetes mellitus develop blinding mature cataracts through the action of the enzyme aldose
Colitz, Carmen   +2 more
core   +1 more source

UBC-Nepal expedition: The use of oral antioxidants does not alter cerebrovascular function at sea-level or high-altitude [PDF]

open access: yes, 2018
Hypoxia is associated with an increased systemic and cerebral formation of free radicals and associated reactants that may be linked to impaired cerebral vascular function a neurological sequela.
Ainslie, Philip   +9 more
core   +1 more source

Efficacy of Using Alpha-Lipoic Acid in Diabetic Neuropathy

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2015
The article presents a review of literature and research demonstrating the effectiveness of using alpha-lipoic acid in diabetic neuropathy.
V.I. Pankiv
doaj   +1 more source

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