Results 111 to 120 of about 3,445,082 (289)

Alpha‐lipoic acid inhibits lung cancer growth via mTOR‐mediated autophagy inhibition

open access: yesFEBS Open Bio, 2020
Lung cancer is the leading cause of cancer‐related death, and there remains a need for novel therapies for this malignancy. Here, we examined the effects of alpha‐lipoic acid (LA), a drug used for treating human diabetic complications, on lung cancer ...
Pei-Pei Peng   +7 more
semanticscholar   +1 more source

Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment [PDF]

open access: yes, 2011
Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods.
Yulia Alexandrovna Trakhtenberg   +1 more
core   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Pengaruh Pemberian Alpha Lipoic Acid terhadap Perbaikan Derajat Distal Symetrical Diabetic Polineurophaty: The Effect of Alpha Lipoic Acid on Improving the Degree of Distal Symetrical Diabetic Polyneurophaty

open access: yes, 2023
Latar belakang: Diabetes Mellitus (DM) adalah penyakit gangguan metabolik yang ditandai oleh kenaikan gula darah akibat penurunan sekresi insulin oleh sel beta pankreas dan atau gangguan fungsi insulin (resistensi insulin), serta menyebabkan kerusakan ...
Anastasia Juliana   +7 more
core   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

open access: yesBiological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century

open access: yesChemistry – A European Journal, EarlyView.
This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza   +2 more
wiley   +1 more source

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

open access: yes, 2010
Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells.
3750   +19 more
core  

Antimicrobial Effect of Alpha Lipoic Acid Against Oral Microorganisms. [PDF]

open access: yes, 2020
Aim: This study was aimed to assess the antibacterial effect of alpha lipoic acids against various oral microorganisms. Background: Oral microorganisms are responsible for oral related diseases.Oral microorganisms implicated in the etiology of dental ...
S , SHEBI, D, EZHILARASAN
core  

Assessment anti-granuloma activity of Alpha-lipoic acid in chicks’ models [PDF]

open access: yes, 2023
Background: Alpha-lipoic acid is an anti-inflammatory and antioxidant agent that has free radical scavenging characteristics as well as better effects on the recycling of other cellular antioxidants.Aim: The present study was made to assess the anti ...
Abdul-Ghani, MR, Naser, AS
core  

Lignocellulosic Triboelectric Materials for Energy Harvesting and Emerging Applications: A Review on Lignin‐Molecular Engineering toward Improved Performance

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Contrasting sustainable biomass with depleting petroleum resources, this review charts the evolutionary timeline of lignin‐based TENGs. We systematically evaluate their fundamental mechanisms, enhancement strategies, and applications in green self‐powered electronics.
Yuxin Yang   +9 more
wiley   +1 more source

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