Results 121 to 130 of about 3,445,082 (289)

The impact of alpha-lipoic acid on amikacin-induced nephrotoxicity

Renal Failure, 2014
Amikacin (AK) is an antibacterial drug, but it has remarkable nephrotoxic and ototoxic side effects due to increase in reactive oxygen radicals. This study was established to determine the possible protective effects of alpha-lipoic acid (ALA), a powerful antioxidant, on AK-induced nephrotoxicity.
AŞCI, Halil, İLHAN, İlter, CANKARA, Fatma Nihan, YEŞİLOT, Sukriye, BAYRAM, Dilek, SAYGIN, Mustafa, CANDAN, Ibrahim Aydin   +6 more
openaire   +5 more sources

Myoinositol combined with alpha-lipoic acid may improve the clinical and endocrine features of polycystic ovary syndrome through an insulin-independent action

, 2017
The aim of our study was to investigate the effects of a combined treatment with alpha-lipoic acid (ALA) and myoinositol (MYO) on clinical, endocrine and metabolic features of women affected by polycystic ovary syndrome (PCOS). In this pilot cohort study,
Apa, Rosanna, Scarinci, Elisa, Tagliaferri, Valeria, Policola, Caterina, Tropea, Anna, Della Casa, Silvia, Romualdi, Daniela, Lanzone, Antonio   +7 more
core   +1 more source

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

European Journal of Organic Chemistry, EarlyView.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau, Maxime Riberaud, Frédéric Taran, Antoine Sallustrau   +3 more
wiley   +1 more source

THE PROTECTIVE EFFECT OF ALPHA LIPOIC ACID ON RETINAL DAMAGE IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

, 2021
In this study, we examined the effects of alpha lipoic acid treatment on streptozotocin (STZ)-induced diabetic rats and investigated the mechanisms underlying the protective action of alpha lipoic acid in diabetic retinal damage which was induced by ...
Yildirim, Metin, Berköz, Mehmet, BAHAR, LEYLA, SUCU, NEHİR, YALIN, ALİ ERDİNÇ, İlhan, Mert   +5 more
core   +1 more source

Effect of α-lipoic acid on the removal of arsenic from arsenic-loaded isolated liver tissues of rat

Bangladesh Journal of Pharmacology, 2006
The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, several antioxidants such as beta-carotene, ascorbic acid, alpha-tocopherol, zinc and selenium had been suggested in the treatment of chronic arsenic ...
Noor- E-Tabassum
doaj  

Histological Study on The Effect of Tamoxifen on The Retina of Adult Male Albino Rats and The Potential Ameliorative Effect of Alpha Lipoic Acid [PDF]

Ain Shams Medical Journal
Background: Tamoxifen is used in cases of gynecomastia, benign prostatic hyperplasia and breast cancer. Alpha-lipoic acid (ALA) is a natural antioxidant found in human diet.
Nehal El-Helbawy
doaj   +1 more source

Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?

Oxidative Medicine and Cellular Longevity, 2019
Alzheimer's disease (AD) is a neurodegenerative disorder characterised by impairments in the cognitive domains associated with orientation, recording, and memory.
S. M. dos Santos, Camila Fernanda Rodrigues Romeiro, Caroline Azulay Rodrigues, A. Cerqueira, M. Monteiro   +4 more
semanticscholar   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Enhanced Degradation of Vinyl Copolymers Based on Lipoic Acid

Journal of Polymer Science, Volume 63, Issue 6, Page 1345-1351, 15 March 2025.
ABSTRACT The introduction of degradable units into the backbone of commodity vinyl polymers represents a major opportunity to address the societal challenge of plastic waste and polymer recycling. Previously, we reported the facile copolymerization of α‐lipoic acid derivatives containing 1,2‐dithiolane rings with vinyl monomers leading to the ...
Yoichi Okayama, Parker Morris, Kaitlin Albanese, Sarah Olsen, Atsunori Mori, Javier Read de Alaniz, Christopher M. Bates, Craig J. Hawker   +7 more
wiley   +1 more source

Effect of the Administration of Alpha-Lipoic Acid on Contrast Sensitivity in Patients with Type 1 and Type 2 Diabetes

Mediators of Inflammation, 2014
The aim of this study was to estimate the effects of oral supplementation of alpha-lipoic acid (ALA) on contrast sensitivity (CS) in patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM).
Anna Gębka, Ewelina Serkies-Minuth, Dorota Raczyńska   +2 more
doaj   +1 more source