Results 131 to 140 of about 3,445,082 (289)

α-lipoic acid suppresses neuronal excitability and attenuates colonic hypersensitivity to colorectal distention in diabetic rats

open access: yes, 2017
Yan Sun,1,* Pan-Pan Yang,1,* Zhen-Yuan Song,2 Yu Feng,1 Duan-Min Hu,1 Ji Hu,1 Guang-Yin Xu,3 Hong-Hong Zhang1,3 1Department of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 2Department of ...
Hu DM   +7 more
core  

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

Hypotensive effect of alpha-lipoic acid after a single administration in rats [PDF]

open access: yes, 2016
Objective: The effect of alpha-lipoic acid on blood pressure was investigated many times in chronic studies, but there are no studies on the effect of this compound after a single administration.
Razny, Katarzyna   +6 more
core   +1 more source

Gut Microbiome Functional Reprogramming Reflects Divergent Social Strategies in a Wild Primate

open access: yesIntegrative Zoology, EarlyView.
Wild golden snub‐nosed monkeys employ divergent social strategies, forming reproductive one‐male units and bachelor all‐male units. We reveal that these social structures, intertwined with seasonal diets, drive distinct functional reprogramming in their gut microbiomes. This adaptive microbial plasticity plays a crucial role in primate socio‐ecological
Guanwei Lan   +11 more
wiley   +1 more source

Effects of Alpha-Lipoic Acids on Sperm Membrane Integrity during Liquid Storage of Boar Semen

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Preliminary studies have shown that sperm membrane from swine shows high sensitivity to cryopreservation process, causing a dramatic reduction in sperm quality.
Laura Parlapan Pîndaru   +1 more
doaj  

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

open access: yesClinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole   +4 more
wiley   +1 more source

Alpha lipoic acid combined with epalrestat: a therapeutic option for patients with diabetic peripheral neuropathy

open access: yes, 2018
Xiaotong Wang,1,* Haixiong Lin,2,* Shuai Xu,3 Yuanlin Jin,1 Ren Zhang4 1Shenzhen Bao’an Traditional Chinese Medicine Hospital Group, Guangzhou University of Chinese Medicine, Shenzhen 518133, People’s Republic of China; 2The First School of ...
Jin YL, Lin HX, Wang XT, Xu S, Zhang R
core  

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

open access: yesJournal of Diabetes Investigation, EarlyView.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh   +13 more
wiley   +1 more source

Alpha-lipoic acid intoxication in an adolescent girl:Case report and review of the literature [PDF]

open access: yes, 2020
Alpha-lipoic acid is a widely used medication that does not need a prescription. Although it is safely used in adults, hitherto no safe dose for children has been reported, and there is no known antidote.
Polat, Sinem   +2 more
core   +1 more source

The synthesis of the enantiomers of lipoic acid [PDF]

open access: yes
Lipoic acid is a biologically important molecule. Whilst the racemate has been available by a number of syntheses for many years, no convenient preparation of the pure enantiomers has so far been described. All the evidence so far presented indicates
Brookes, Michael H.
core  

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