Results 151 to 160 of about 3,445,082 (289)

Alpha-lipoic acid induced insulin autoimmune antibody syndrome

The Egyptian Journal of Internal Medicine
Background Insulin autoimmune antibody syndrome is an uncommon cause of hypoglycemia in non-diabetic individuals. We report a case of alpha-lipoic acid-induced insulin autoimmune antibody syndrome.
Karthik Baburaj, Jabir MP, Vimal MV
doaj   +1 more source

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells.
3750, Kenzo, Uehira, Akiko, Kawabe, Masahito, Suiko, 3748, Kentaro, Nishimoto, Harishkumar, Madhyastha, 3749, Yoichi, Sakakibara, Kazuo, Nishiyama, Taiji, Suda, Masao, Yamasaki, Takeaki, Okamoto, 3751, 3742, 3743, 3744, 3745, 3746, 3747   +19 more
core  

Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye

, 2016
Daniel Sarezky, Aaishah R Raquib, Joshua L Dunaief, Benjamin J Kim Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Purpose: Alpha lipoic acid (ALA) is an antioxidant and ...
Sarezky D, Raquib AR, Kim BJ, Dunaief JL
core  

Efficacy of Using Alpha-Lipoic Acid in Diabetic Neuropathy

, 2015
The article presents a review of literature and research demonstrating the effectiveness of using alpha-lipoic acid in diabetic ...
V.I. Pankiv
core   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Effect of Alpha-lipoic Acid on Memory, Oxidation, and Lifespan in SAMP8 Mice

, 2012
Oxidative damage is associated with neurodegenerative disorders such as Alzheimer\u27s disease (AD). The antioxidant alpha-lipoic acid has been found to improve memory in mouse models of AD.
Farr, Susan A., Price, Tulin O., John E. Morley, Banks, William A., William A. Banks, Morley, John E., Susan A. Farr, Nuran Ercal, Ercal, Nuran, Tulin O. Price   +9 more
core   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source

Effects of Alpha Lipoic Acid Supplementation on Slow Skeletal Muscle Mass and Contractile Functions in Type 2 Diabetic Male Sprague Dawley Rats

Life and Science
Objective: To see the Effects of Alpha-Lipoic Acid (ALA) supplementation on slow skeletal muscle mass and contractile functions in type 2 diabetic male Sprague Dawley rats. Study Design: Quasi-experimental study.
Barkat Ullah Khan, Iftekhar Yousef, Sidra Arshad, Faiza Ikram, Amjad Ali, Ikram Ullah   +5 more
doaj   +1 more source

Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics

Advanced Science, Volume 13, Issue 49, 3 September 2026.
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley   +1 more source

Comprehensive Peptide Profiling Reveals the Influence of Streptococcus Thermophilus, Lactobacillus Delbrueckii Subsp. bulgaricus, and Endogenous Milk Proteases on the Hydrolysis of Milk Proteins During Early‐Stage Lactic Acid Fermentation

ChemFoodChem, Volume 2, Issue 3, September 2026.
Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck, Lena Riedinger, Sevim Dalabasmaz, Joachim Stützer, Luisa Bähr, Rohtraud Pichner, Monika Pischetsrieder   +6 more
wiley   +1 more source