Results 91 to 100 of about 4,202,272 (225)

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan   +23 more
wiley   +1 more source

Effect of the Administration of Alpha-Lipoic Acid on Contrast Sensitivity in Patients with Type 1 and Type 2 Diabetes

open access: yesMediators of Inflammation, 2014
The aim of this study was to estimate the effects of oral supplementation of alpha-lipoic acid (ALA) on contrast sensitivity (CS) in patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM).
Anna Gębka   +2 more
doaj   +1 more source

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau   +3 more
wiley   +1 more source

Lipoic acid: An universal antioxidant [PDF]

open access: yes, 2008
Alfa lipoik asit bazı yiyeceklerde bulunan ve aynı zamanda vücutta sentezlenen doğal bir maddedir. Serbest radikal hasarını önleyen lipoik asit yağda ve suda çözünebilmesi açısından antioksidanlar arasında tektir.
Karaca, E. Gülçin
core   +1 more source

Transformative Masked Ortho‐Quinone Chemistry: From Direct Guaiacol Activation to Lignin‐Based Adhesives

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 43, 19 October 2026.
Renewable guaiacols are rapidly oxidized by phenyliodine(III)diacetate to masked ortho‐quinones, giving a new class of monomers that undergo selective Michael‐type polyaddition with multithiols to from thiol‐guaiacol connectivity‐bearing polymers. The activation applies to discrete monomers and directly to lignin, enabling two‐component adhesives that ...
Dominik P. Hoch   +7 more
wiley   +1 more source

Hypotensive effect of alpha-lipoic acid after a single administration in rats [PDF]

open access: yes, 2016
Objective: The effect of alpha-lipoic acid on blood pressure was investigated many times in chronic studies, but there are no studies on the effect of this compound after a single administration.
Razny, Katarzyna   +6 more
core   +1 more source

Effects of Alpha-Lipoic Acids on Sperm Membrane Integrity during Liquid Storage of Boar Semen

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Preliminary studies have shown that sperm membrane from swine shows high sensitivity to cryopreservation process, causing a dramatic reduction in sperm quality.
Laura Parlapan Pîndaru   +1 more
doaj  

Targeting Oxidative and Immune Dysregulation in Wound Healing via Gold Nanoparticle Conjugate Chitosan

open access: yesThe FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This gold nanoparticle–chitosan (AuNP@chitosan) composite promotes burn wound healing by simultaneously regulating endothelial and immune responses. In vitro, the composite protects TNF‐α‐injured HUVECs by reducing ROS, restoring thrombomodulin, and upregulating hypoxia‐adaptive markers.
Sheng‐Der Hsu   +6 more
wiley   +1 more source

Antimicrobial Effect of Alpha Lipoic Acid Against Oral Microorganisms. [PDF]

open access: yes, 2020
Aim: This study was aimed to assess the antibacterial effect of alpha lipoic acids against various oral microorganisms. Background: Oral microorganisms are responsible for oral related diseases.Oral microorganisms implicated in the etiology of dental ...
S , SHEBI, D, EZHILARASAN
core  

Protection from spinal cord ischemia-reperfusion damage with alpha-lipoic acid preconditioning in an animal model

open access: yes, 2018
Background: This study aims to investigate whether preconditioning with alpha-lipoic acid has any protective effect in neuronal damage in an experimental spinal cord ischemia-reperfusion injury ...
Kaymaz, Memduh   +6 more
core   +1 more source

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