Results 71 to 80 of about 4,202,272 (225)

Encapsulation of alpha-lipoic acid into chitosan and alginate/gelatin hydrogel microparticles and its in vitro antioxidant activity [PDF]

, 2016
Alpha-lipoic acid is an organosulphur compound well-known for its therapeutic potential and antioxidant properties. However, the effective use of alpha-lipoic acid depends on biological plasma half-life and its preserving stability, which could be ...
Milašinović, Nikola, Vidović, Bojana, Kalagasidis-Krušić, Melina T., Kotur-Stevuljević, Jelena, Dilber, Sanda, Kalagasidis Krušić, Melina, Đoržević, Brižita, Knežević-Jugović, Zorica, Đorđević, Brižita, Dilber, Sanda P.   +9 more
core   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

The Application of Lipoic Acid in Experimentally Induced Tympanosclerosis in Rats

Journal of Contemporary Medicine, 2020
Background/Aims:Tympanosclerosisis an abnormal tissue reaction resulting in sclerotic and hyalinization changesin the tympanic membrane and middle ear.We hypothesized that alpha lipoic acid, an antioxidant, may represent asimple and effective form of ...
Fatih Turan, İlyas Sayar, İsmail Salcan   +2 more
doaj   +1 more source

Alpha-lipoic acid for diabetic peripheral neuropathy

Cochrane Database of Systematic Reviews, 2018
Diabetic peripheral neuropathy (DPN) is a frequent complication in people living with type 1 or type 2 diabetes. There is currently no effective treatment for DPN. Although alpha-lipoic acid (ALA, also known as thioctic acid) is widely used, there is no consensus about its benefits and harms.To assess the effects of alpha-lipoic acid as a disease ...
Baicus, Cristian, Purcarea, Adrian, von Elm, Erik, Delcea, Caterina, Furtunescu, Florentina L   +4 more
openaire   +4 more sources

Gut Microbiome Functional Reprogramming Reflects Divergent Social Strategies in a Wild Primate

Integrative Zoology, EarlyView.
Wild golden snub‐nosed monkeys employ divergent social strategies, forming reproductive one‐male units and bachelor all‐male units. We reveal that these social structures, intertwined with seasonal diets, drive distinct functional reprogramming in their gut microbiomes. This adaptive microbial plasticity plays a crucial role in primate socio‐ecological
Guanwei Lan, Xianjun Li, Zhantao Lu, Yue Zhang, Feifei Feng, Juan Liu, Wei Wu, Jiabin Liu, Yanshan Zhou, Jiang Gu, Rui Ma, Dunwu Qi   +11 more
wiley   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

The FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson, Kai‐Christian Sonntag, Thao Do Vy Le, Kaitlin Shannon, Chao Wang, Fei Du, Xi Chen, Donna McPhie, Dost Ongur, Bruce Cohen, Virginie‐Anne Chouinard   +10 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

The use of rosuvastatin and alpha lipoic acid in patients with unstable angina

Acta Medica Leopoliensia, 2017
Aim. To investigate the blood lipid profile, indices of functional condition of the liver in patients with unstable angina in the treatment of statins in combination with alpha lipoic acid.  Material and Methods.
E.H. Zaremba, O.V. Smalyukh, O.V. Zaremba-Fedchyshyn, O.V. Zaremba   +3 more
doaj   +1 more source

Family Impact of Burning Mouth Syndrome: A Cross‐Sectional Study Using FROM‐16

Oral Diseases, EarlyView.
ABSTRACT Background Burning mouth syndrome (BMS) is a chronic oral pain condition associated with psychological distress and reduced quality of life. Although BMS' impact on patients is documented, family member impact remains poorly understood. This study evaluated family impact using Family Reported Outcome Measure (FROM‐16), explored family burden ...
Mona Jullie Hajj, Nicholas Sotak, Alessandro Villa, Alan Roger Santos‐Silva, Lloyd Mancl, Thaís Cristina Esteves‐Pereira, Milda Chmieliauskaite   +6 more
wiley   +1 more source