Results 81 to 90 of about 4,202,272 (225)

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker   +7 more
wiley   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy   +7 more
wiley   +2 more sources

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

open access: yesBiological Reviews, Volume 101, Issue 6, Page 2780-2795, December 2026.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Reduction of Conjunctival Fibrosis After Trabeculectomy Using Topical alpha-Lipoic Acid in Rabbit Eyes

open access: yes, 2014
Purpose: To evaluate the efficacy of alpha-lipoic acid (ALA) in reducing scarring after ...
KELEŞ, Sadullah   +8 more
core   +1 more source

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

open access: yes
Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells.
3750   +19 more
core   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao   +5 more
wiley   +1 more source

Baseline differences in clinical and biochemical characteristics according to the use of alpha-lipoic acid.

open access: yes, 2016
Baseline differences in clinical and biochemical characteristics according to the use of alpha-lipoic acid.
Ja-Hae Kim (3139734)   +10 more
core   +1 more source

Lactobacillus‐Loaded Bioadhesive Hydrogel with Prolonged Retention and Microenvironmental Remodeling for Endometrial Repair and Fertility Restoration

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Lifa Chen   +9 more
wiley   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2409-2419, November 2026.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco   +6 more
wiley   +1 more source

Histological Study on The Effect of Tamoxifen on The Retina of Adult Male Albino Rats and The Potential Ameliorative Effect of Alpha Lipoic Acid [PDF]

open access: yesAin Shams Medical Journal
Background: Tamoxifen is used in cases of gynecomastia, benign prostatic hyperplasia and breast cancer. Alpha-lipoic acid (ALA) is a natural antioxidant found in human diet.
Nehal El-Helbawy
doaj   +1 more source

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