Results 71 to 80 of about 26,643 (286)

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

Advanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang, Jie Chen, Yunmiao Ma, Qingwei Zhou, Yu Kong, Yingxiang Chen, Junjie Chi, Haihua Hu   +7 more
wiley   +1 more source

Endothelial dysfunction in type 2 diabetes: effect of antioxidants [PDF]

, 2007
Individuals with insulin resistance and diabetes mellitus have increased cardiovascular morbidity and mortality, caused in part by vascular complications. Endothelial dysfunction has been implicated in the pathogenesis of vascular diabetic disease.
Louro, T, Nunes, E, Proença, T, Seiça, RM, Sena, CM   +4 more
core  

Dihydrolipoic acid reduces cytochrome b561 proteins. [PDF]

, 2013
Cytochrome b561 (Cyt-b561) proteins constitute a family of trans-membrane proteins that are present in a wide variety of organisms. Two of their characteristic properties are the reducibility by ascorbate (ASC) and the presence of two distinct b-type ...
A Bast, A Bérczi, A Bérczi, A Bérczi, A Bérczi, A Bérczi, A Glanfield, A Mizutani, AA Herbert, Alajos Bérczi, AT McKie, AV Kozlov, C Sgherri, D Griesen, D Han, D Zhang, E Okuyama, ELR Stokstad, ER Henry, F Desmet, GE Tusnády, GE Tusnády, GP Biewenga, GP Biewenga, H Asard, H Kataoka, H Scholich, Han Asard, J Lykkesfeldt, JCH Shih, JS Oakhill, L Cenacchi, L Packer, L Packer, L Packer, L Zimányi, LJ Reed, László Zimányi, M Lakshminarasimhan, M Srivastava, M Tsubaki, M Tsubaki, MAK Markwell, MC Recuenco, O Terland, PJ Fleming, PM Kelley, R Yasuno, RI Shrager, S Ludwiczek, SJ Booker, T Flatmark, TW Nichols, U Pérez-López, UM Kent, V Preger, VE Kagan, W Liu, W Liu, W Verelst, Y Li, Y Nanasato   +61 more
core   +1 more source

From Light‐Driven to Dark Synthesis: Streamlining Perfluoroalkyl Selenide Ether Formation

European Journal of Organic Chemistry, EarlyView.
Two orthogonal and user‐friendly protocols enable the efficient construction of (Se/S)RF bonds from simple dichalcogenides and perfluoroalkyl iodides. Visible‐light irradiation at 395 nm promotes seleno‐ and thioether formation, while a dark KOH/MeCN variant delivers selenoethers in minutes. Both approaches operate under mild, metal‐ and photocatalyst‐
Loydel Torres Barroso, Romina S. Conde, Damian E. Yerien, Agustin A. Zottola, Al Postigo, Sebastian Barata‐Vallejo   +5 more
wiley   +1 more source

Alpha lipoic acid in obstetrics and gynecology

Gynecological Endocrinology, 2018
Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this review, we analyzed the action of ALA in gynecology and obstetrics focusing in particular on neuropathic pain and antioxidant and anti-inflammatory action.
Di Tucci, Chiara, Di Feliciantonio, Mara, Vena, Flaminia, Capone, Carmela, Schiavi, Michele Carlo, Pietrangeli, Daniela, Muzii, Ludovico, Benedetti Panici, Pierluigi   +7 more
openaire   +3 more sources

Thermoregulatory and cardiovascular responses to creatine, glycerol and alpha lipoic acid in trained cyclists [PDF]

, 2012
Background It has been shown that supplementation with creatine (Cr) and glycerol (Gly), when combined with glucose (Glu) necessary for the enhancement of Cr uptake by skeletal muscle, induces significant improvements in thermoregulatory and ...
Hambly, C., Lee, W.C., Malkova, D., Pantazis, T., Pitsiladis, Y.P., Polyviou, T.P., Speakman, J.R.   +6 more
core   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products [PDF]

, 2016
The increasing incidence of autism suggests a major environmental influence. Epidemiology has implicated many candidates and genetics many susceptibility genes.
Blizard, RA, Carter, CJ
core   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source