Results 111 to 120 of about 16,063 (220)

Achieving and Maintaining Cognitive Vitality With Aging [PDF]

, 2001
This report contains the summary results of a workshop held at Canyon Ranch Health Resort in Tucson, Arizona. Physicians and scientists shed light on the process of cognitive aging.
Howard Fillit, Robert N. Butler
core  

Inhibition of Notch signaling affects hepatic oval cell response in rat model of 2AAF-PH

Hepatic Medicine: Evidence and Research, 2011
Houda Darwiche, Seh-Hoon Oh, Nicole C Steiger-Luther, Jennifer M Williams, Dana G Pintilie, Thomas D Shupe, Bryon E PetersenDepartment of Pathology, Immunology, and Laboratory Medicine, Program in Stem Cell Biology and Regenerative Medicine, College of ...
Darwiche H, Oh S-H, Steiger-Luther NC, Williams JM, Pintilie DG, Shupe TD, Petersen BE   +6 more
doaj  

Structure and function of voltage-gated sodium channel Nav1.6: Involvement in the pathological process of neural injury

Neural Regeneration Research
The voltage-gated sodium channel Nav1.6, encoded by the sodium voltage-gated channel alpha subunit 8 gene, is a crucial regulator of neuronal excitability, with widespread expression throughout the central and peripheral nervous systems.
Huaiyuan Wang, Yuhang Wei, Junqi Wang, Jiyuan Liu, Shaowu Ou, Jun Wang   +5 more
doaj   +1 more source

Effects of antihypertensive agents on Alzheimer’s disease biomarkers in hypertensive rats with experimentally induced Alzheimer’s

Zanco Journal of Medical Sciences
Background and objective: The most common cause of dementia in the elderly is Alzheimer's disease (AD). Numerous research studies have demonstrated a connection between hypertension (HTN) and the risk of developing AD.
Marwan Qasim Nadir, Rojgar Hamed Ali
doaj   +1 more source

Alzheimer's disease immunization strategies : a review of current research [PDF]

, 2009
Scholarly project (M.S.)
Sirgedas, Laura Ona
core   +1 more source

BACE2 tunes lipid uptake through lipid transporters shedding supporting cancer cell proliferation

Journal of Experimental & Clinical Cancer Research
Background Lipids play crucial roles in signal transduction, membrane integrity, and energy metabolism. In cancer, lipid metabolism is frequently dysregulated. Proliferating cancer cells exhibit enhanced lipid uptake, synthesis, and storage; however, the
Vittoria Matafora, Alice Elhagh, Alessandra Morelli, Laura Tronci, Angela Cattaneo, Camilla Conti, Francesca Casagrande, Francesco Farris, Angela Bachi   +8 more
doaj   +1 more source

Effects of DHA and EGCG on the alpha-secretase mediated processing of APP

, 2015
Therapeutic strategies currently used for Alzheimer's disease (AD) are ineffective at stopping disease progression and result in side effects which may further degrade the quality of life for those suffering with the debilitating disease. Until more promising drugs are developed and tested, finding ways to reduce the risk of disease and development may
openaire   +1 more source

The overall structure of the multi-domain amyloid precursor protein [PDF]

, 2013

core   +1 more source

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source

The role of Notch signalling and its crosstalk with oestrogen receptor signalling in breast cancer. [PDF]

Cancer Metastasis Rev
Azadova A, Isayev O, Marco A, Brooke GN.
europepmc   +1 more source