Results 201 to 210 of about 16,063 (220)

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Nature, 2020
Ji-Yeun Hur, Eitan Wong, Marilia Barros
exaly  

Alzheimer’s-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

Cell, 2017
Maria Szaruga, Bogdan Munteanu, Natalie S Ryan   +2 more
exaly  

Phlorotannin-rich Ecklonia cava reduces the production of beta-amyloid by modulating alpha- and gamma-secretase expression and activity

NeuroToxicology, 2013
Il Jun Kang, Min-Ju Kim, Misook Kim
exaly  

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Science, 1999
Robert Vassar, David B Teplow, Martin Citron   +2 more
exaly  

Regulation of Alpha-Secretase ADAM10 In vitro and In vivo: Genetic, Epigenetic, and Protein-Based Mechanisms

Frontiers in Molecular Neuroscience, 2017
Kristina Endres, Thomas Deller
exaly  

Recognition of the amyloid precursor protein by human γ-secretase

Science, 2019
Rui Zhou, Guanghui Yang, Xuefei Guo
exaly  

Purification and cloning of amyloid precursor protein β-secretase from human brain

Nature, 1999
Varghese John
exaly  

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Nature, 1999
Michael S Wolfe, Weiming Xia, W Taylor Kimberly   +2 more
exaly  

O3‐05–02: EHT‐0202: A neuroprotective and procognitive alpha‐secretase stimulator targeted towards Alzheimer disease therapy

Alzheimer's & Dementia, 2008
Laurent Desire, Luc Buee, Nathalie Lambeng, Dominique Drouin, Fabien Schweighoffer   +4 more
openaire   +1 more source

P4-400 Alpha secretase activity is selectively activated by the 5-HT4 receptor through EPAC and RAC

Neurobiology of Aging, 2004
Sylvain Robert, Marjorie Maillet, Eric Morel, Rodolphe Fischmeister, Luc Mercken, Frank Lezoualc'h   +5 more
openaire   +1 more source