Alpha7 nicotinic receptors as potential theranostic targets for experimental stroke. [PDF]
Neural Regen Res, 2023 Garbizu M, Aguado L, Martín A.
europepmc +3 more sources
Psychopharmacology, 2021 There are controversial pieces of evidence whether combination therapies using memantine and cholinesterase inhibitors are beneficial over their monotreatments.
Nóra Bruszt +4 more
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Single particle tracking of alpha7 nicotinic AChR in hippocampal neurons reveals regulated confinement at glutamatergic and GABAergic perisynaptic sites. [PDF]
PLoS ONE, 2010 Alpha7 neuronal nicotinic acetylcholine receptors (alpha7-nAChR) form Ca(2+)-permeable homopentameric channels modulating cortical network activity and cognitive processing.
Thomas Bürli +5 more
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Frontiers in Pharmacology, 2021 The α7 nicotinic acetylcholine receptor (α7nAChR) belongs to the superfamily of cys loop cationic ligand-gated channels, which consists of homogeneous α7 subunits.
Zhe‐Qi Xu +7 more
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[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys. [PDF]
PLoS ONE, 2008 BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease.
Kenji Hashimoto +8 more
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Cholinergic anti-inflammatory pathway and COVID-19 [PDF]
BioImpacts, 2022 The cholinergic anti-inflammatory pathway (CAP) first described by Wang et al, 2003 has contemporary interest arising from the COVID-19 pandemic. While tobacco smoking has been considered an aggravating factor in the severity of COVID-19 infections, it ...
Danial Mehranfard, Robert C. Speth
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Nicotine acts on growth plate chondrocytes to delay skeletal growth through the alpha7 neuronal nicotinic acetylcholine receptor. [PDF]
PLoS ONE, 2008 BACKGROUND: Cigarette smoking adversely affects endochondral ossification during the course of skeletal growth. Among a plethora of cigarette chemicals, nicotine is one of the primary candidate compounds responsible for the cause of smoking-induced ...
Atsuo Kawakita +6 more
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Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels [PDF]
Brain Research, 2009 Studies using the radio-labeled nicotinic receptor antagonist [(125)I]-alpha-bungarotoxin, which binds to alpha7 subunit containing nicotinic receptors, have demonstrated that mouse strains vary considerably in the number of alpha7-containing nicotinic receptors in brain.
Nathanial P, Brooks +2 more
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Upregulation of alpha7 Nicotinic Receptors by Acetylcholinesterase C-Terminal Peptides. [PDF]
PLoS ONE, 2009 BACKGROUND: The alpha-7 nicotinic acetylcholine receptor (alpha7-nAChR) is well known as a potent calcium ionophore that, in the brain, has been implicated in excitotoxicity and hence in the underlying mechanisms of neurodegenerative disorders such as ...
Cherie E Bond +2 more
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In vivo evaluation of alpha7 nicotinic acetylcholine receptor agonists [11C]A-582941 and [11C]A-844606 in mice and conscious monkeys. [PDF]
PLoS ONE, 2010 BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease.
Jun Toyohara +6 more
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