Results 141 to 150 of about 2,375 (163)
Some of the next articles are maybe not open access.
ACS Pharmacology & Translational Science, 2023
Alpha7 nicotinic acetylcholine receptor (α7 nAChR) is an ion-gated calcium channel that plays a significant role in various aspects of cancer pathogenesis, particularly in lung cancer. Preclinical studies have elucidated the molecular mechanism underlying α7 nAChR-associated lung cancer proliferation, chemotherapy resistance, and metastasis ...
Kuntarat Arunrungvichian +3 more
openaire +2 more sources
Alpha7 nicotinic acetylcholine receptor (α7 nAChR) is an ion-gated calcium channel that plays a significant role in various aspects of cancer pathogenesis, particularly in lung cancer. Preclinical studies have elucidated the molecular mechanism underlying α7 nAChR-associated lung cancer proliferation, chemotherapy resistance, and metastasis ...
Kuntarat Arunrungvichian +3 more
openaire +2 more sources
Journal of Neurophysiology, 2014
The dorsal raphe nucleus (DRN) contains large populations of serotonergic (5-HT) neurons. This nucleus receives GABAergic inhibitory afferents from many brain areas and from DRN interneurons. Both GABAergic and 5-HT DRN neurons express functional nicotinic acetylcholine receptors (nAChRs). Previous studies have demonstrated that nicotine increases 5-HT
F, Hernández-Vázquez +4 more
openaire +2 more sources
The dorsal raphe nucleus (DRN) contains large populations of serotonergic (5-HT) neurons. This nucleus receives GABAergic inhibitory afferents from many brain areas and from DRN interneurons. Both GABAergic and 5-HT DRN neurons express functional nicotinic acetylcholine receptors (nAChRs). Previous studies have demonstrated that nicotine increases 5-HT
F, Hernández-Vázquez +4 more
openaire +2 more sources
Brain Research Bulletin, 2004
Alpha7 nicotinic acetylcholine receptors (nAChRs) play a role in axonogenesis, synaptogenesis and synaptic plasticity, and are therefore potential targets for developmental neurotoxicants. We administered nicotine to neonatal rats during discrete periods spanning the onset and peak of axonogenesis/synaptogenesis, focusing on three brain regions with ...
Theodore A, Slotkin +4 more
openaire +2 more sources
Alpha7 nicotinic acetylcholine receptors (nAChRs) play a role in axonogenesis, synaptogenesis and synaptic plasticity, and are therefore potential targets for developmental neurotoxicants. We administered nicotine to neonatal rats during discrete periods spanning the onset and peak of axonogenesis/synaptogenesis, focusing on three brain regions with ...
Theodore A, Slotkin +4 more
openaire +2 more sources
Targeting alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia.
Current pharmaceutical design, 2010The most abundant homomeric nicotinic acetylcholine receptors (nAChRs) in the mammalian brain are the pentameric alpha7 nAChRs which consist of five alpha7 subunits, and each subunit provides an orthosteric low affinity binding site for its endogenous ligand, acetylcholine.
Mihály, Hajós, Bruce N, Rogers
openaire +1 more source
Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor
Journal of Medicinal Chemistry, 2008Ramin, Faghih +2 more
openaire +2 more sources
The role of alpha7 nicotinic acetylcholine receptors in B lymphocyte activation.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 2010The involvement of nicotinic acetylcholine receptor (nAChR) a7 subtype in B lymphocyte activation has been investigated. B lymphocytes were magnetically separated from the spleens of C57Bl/6J mice. The purified lymphocytes were treated with fluorescently labeled IgM-, CD40-, CD16/32 or CD23-specific antibodies and unlabeled alpha7-specific antibody and
L M, Koval +4 more
openaire +1 more source
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly