Results 61 to 70 of about 2,375 (163)
Ly6h Regulates Trafficking of Alpha7 Nicotinic Acetylcholine Receptors and Nicotine-Induced Potentiation of Glutamatergic Signaling [PDF]
α7 nAChRs are expressed widely throughout the brain, where they are important for synaptic signaling, gene transcription, and plastic changes that regulate sensory processing, cognition, and neural responses to chronic nicotine exposure. However, the mechanisms by which α7 nAChRs are regulated are poorly understood.
Clare A, Puddifoot +3 more
openaire +2 more sources
Paraprobiotics are nonvital bacteria that have health benefits. Recently, they have been incorporated into dairy products as supplements to probiotics. The advantages of using paraprobiotics mainly include superior resistance to processing conditions, extended shelf‐life, and safer consumption by people with weaker immune systems.
Seyed Ali Issazadeh +2 more
wiley +1 more source
Neuronal and Glial α7 Nicotinic Acetylcholine Receptors: Role in Alzheimer’s Disease Pathophysiology
Cholinergic projections from the basal forebrain to the cortex and hippocampus play a critical role in cognitive functions, many of which rely on signaling through the alpha7 nicotinic acetylcholine receptor (α7nAChR).
Kerry Rennie
doaj +1 more source
Mechanisms of citicoline in treating neuroinflammatory disorders. Abstract Citicoline, a compound produced naturally in small amounts in the human body, assumes a pivotal role in phosphatidylcholine synthesis, a dynamic constituent of membranes of neurons.
Simona Cavalu +6 more
wiley +1 more source
Reproduction in Domestic Animals, Volume 58, Issue S1, Page 3-38, February 2023.
wiley +1 more source
Adipose-derived stem cells (ASCs) are an attractive source for regenerative medicine as they can be easily isolated, rapidly expandable in culture and show excellent in vitro differentiation potential.
Marta Pernarella +8 more
doaj +1 more source
GSK3: A potential target and pending issues for treatment of Alzheimer's disease
GSK3 signaling in Alzheimer's disease and targeted therapies. Abstract Glycogen synthase kinase‐3 (GSK3), consisting of GSK3α and GSK3β subtypes, is a complex protein kinase that regulates numerous substrates. Research has observed increased GSK3 expression in the brains of Alzheimer's disease (AD) patients and models.
Jiahui Zhao +6 more
wiley +1 more source
Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice
Abstract The alpha7 nicotinic acetylcholine receptor (α7 nAChR; CHRNA7) is expressed in the nervous system and in non‐neuronal tissues. Within the central nervous system, it is involved in various cognitive and sensory processes such as learning, attention, and memory.
Karolina Magdalena Caban +5 more
wiley +1 more source
Comprehensive view of macrophage autophagy and its application in cardiovascular diseases
This review systematically describes the role of autophagy in macrophage functions, highlighting the existing evidence in the regulation of inflammation, cell death, metabolism, phagocytosis, and so forth. Meanwhile, we summarize the latest progress of therapeutics targeting macrophage autophagy in cardiovascular diseases, hoping to provide novel ...
Wanqian Pan +10 more
wiley +1 more source
Role of Nicotinic Acetylcholine Receptor α3 and α7 Subunits in Detrusor Overactivity Induced by Partial Bladder Outlet Obstruction in Rats [PDF]
Purpose: To investigate the role of α3 and α7 nicotinic acetylcholine receptor subunits (nAChRs) in the bladder, using a rat model with detrusor overactivity induced by partial bladder outlet obstruction (BOO).
Hyo Sin Kim +5 more
doaj +1 more source

