Results 71 to 80 of about 1,282,638 (192)
The role of neuronal nicotinic acetylcholine receptors in central cardiovascular regulation. [PDF]
, 2007 The central effect of nicotine on cardiovascular regulation has been extensively studied. However, due to its unselective nature for nicotinic acetylcholine receptors (nAChR) the involvement of specific nAChRs at sites in the brain, in central nervous ...
Moore, C.
core
The FASEB Journal, Volume 38, Issue 17, September 2024.Mechanisms of citicoline in treating neuroinflammatory disorders. Abstract Citicoline, a compound produced naturally in small amounts in the human body, assumes a pivotal role in phosphatidylcholine synthesis, a dynamic constituent of membranes of neurons.
Simona Cavalu +6 more
wiley +1 more source
, 2023 Reproduction in Domestic Animals, Volume 58, Issue S1, Page 3-38, February 2023.
wiley +1 more source
Impaired Hippocampal Theta Oscillations in the Mice Null Alpha7 Nicotinic Acetylcholine Receptors [PDF]
CNS Neuroscience & Therapeutics, 2013 Nicotinic acetylcholine receptor (nAChR) a7 subunits are among the most ancient of vertebrate nAChR subunits and have the capacity to assemble as homomers. Naturally expressed a7-nAChRs in the central nervous system play a critical role in modulating the release of various neurotransmitters, neurite outgrowth, and even neuronal survival or death [1 ...
Yu, Jin +4 more
openaire +2 more sources
Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects. [PDF]
, 2015 Activation of nicotinic acetylcholine receptors (nAChRs) is associated with the binding of agonists such as acetylcholine to an extracellular site that is located at the interface between two adjacent receptor subunits.
Dhankher, P +4 more
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The alpha7 nicotinic acetylcholine receptor: molecular modelling, electrostatics, and energetics.
, 2005 The structure of a homopentameric alpha7 nicotinic acetylcholine receptor is modelled by combining structural information from two sources: the X-ray structure of a water soluble acetylcholine binding protein from Lymnea stagnalis, and the electron ...
Sansom, MS +5 more
core +1 more source
GSK3: A potential target and pending issues for treatment of Alzheimer's disease
CNS Neuroscience &Therapeutics, Volume 30, Issue 7, July 2024.GSK3 signaling in Alzheimer's disease and targeted therapies. Abstract Glycogen synthase kinase‐3 (GSK3), consisting of GSK3α and GSK3β subtypes, is a complex protein kinase that regulates numerous substrates. Research has observed increased GSK3 expression in the brains of Alzheimer's disease (AD) patients and models.
Jiahui Zhao +6 more
wiley +1 more source
Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice
PROTEOMICS, Volume 24, Issue 10, May 2024.Abstract The alpha7 nicotinic acetylcholine receptor (α7 nAChR; CHRNA7) is expressed in the nervous system and in non‐neuronal tissues. Within the central nervous system, it is involved in various cognitive and sensory processes such as learning, attention, and memory.
Karolina Magdalena Caban +5 more
wiley +1 more source
Loop B is a major structural component of the 5-HT3 receptor [PDF]
, 2008 The 5-HT3 receptor belongs to a family of therapeutically important neurotransmitter-gated receptors whose ligand binding sites are formed by the convergence of six peptide loops (A-F).
Thompson, Andrew J. +9 more
core +2 more sources
European Journal of Histochemistry, 2020 Adipose-derived stem cells (ASCs) are an attractive source for regenerative medicine as they can be easily isolated, rapidly expandable in culture and show excellent in vitro differentiation potential.
Marta Pernarella +8 more
doaj +1 more source