Results 21 to 30 of about 65,682 (262)

Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling

open access: yesCells, 2023
The deregulation in the Wnt/β-catenin signaling pathway is associated with many human cancers, particularly colorectal cancer (CRC) and, therefore, represents a promising target for drug development.
Xi Chen   +10 more
doaj   +1 more source

Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. [PDF]

open access: yesPLoS ONE, 2011
The large conductance calcium-activated potassium channel alpha-subunit (Slo) is widely distributed throughout the body and plays an important role in a number of diseases.
Shumin Bian   +7 more
doaj   +1 more source

Cinnamaldehyde Relieves Induced Hepatocellular Carcinoma in Rat Model via Targeting Wnt/β-Catenin Pathway

open access: yesScientia Pharmaceutica, 2022
Cinnamaldehyde (CA) is a natural compound that has promising biological activity. The current study investigates the antitumor activity of CA in thioacetamide induced hepatocellular carcinoma (HCC) in rats through targeting the Wnt/β-catenin pathway and ...
Al Shaima G. Abd El Salam   +2 more
doaj   +1 more source

Vanadium-protein complex inhibits human adipocyte differentiation through the activation of β-catenin and LKB1/AMPK signaling pathway.

open access: yesPLoS ONE, 2020
Obesity is a common disease over the world and is tightly associated with diabetes mellitus, cardiovascular and cancer disease. Although our previous study showed that the synthetic vanadium-protein (V-P) complex had a better effect on antioxidant and ...
Shuang Zhang, Lei Yan, Sang Moo Kim
doaj   +1 more source

Involvement of the Wnt/β-catenin signaling pathway in the cellular and molecular mechanisms of fibrosis in endometriosis. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:During the development and progression of endometriotic lesions, excess fibrosis may lead to scarring, chronic pain, and altered tissue function.
Sachiko Matsuzaki, Claude Darcha
doaj   +1 more source

Application of on-line nanoLC-IT-TOF in the identification of serum β-catenin complex in mice scald model. [PDF]

open access: yesPLoS ONE, 2012
Severe burn shock remains an unresolved clinical problem with an urgent need to explore novel therapeutic treatments. Intracellular β-catenin, through interaction with other proteins, has been reported to be able to regulate the size of cutaneous wounds.
Cheng-cai Huang   +4 more
doaj   +1 more source

Analysis of expression profile of genes encoding cell adhesion proteins in endometrial cancer

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2012
Endometrial cancer is one of the most common gynecological malignancies. Unfortunately, molecular pathogenesis of this neoplasm remains poorly understood.
Tomasz Kubiatowski   +4 more
doaj   +1 more source

Cx43, ZO-1, alpha-catenin and beta-catenin in cataractous lens epithelial cells

open access: yesJournal of Biosciences, 2012
Specimens of the anterior lens capsule with an attached monolayer of lens epithelial cells (LECs) were obtained from patients (n=52) undergoing cataract surgery. Specimens were divided into three groups based on the type of cataract: nuclear cataract, cortical cataract and posterior subcapsular cataract (PSC).
Anshul I, Arora   +8 more
openaire   +2 more sources

Venlafaxine Inhibits the Apoptosis of SHSY-5Y Cells Through Active Wnt/β-Catenin Signaling Pathway

open access: yesNeuropsychiatric Disease and Treatment, 2021
Ruijie Geng,1 Haibin Li,1 Hao Wang,2 Chenyu Ye,1 Yemeng Mao,3 Xiao Huang1,4 1Department of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Teaching Center of Experimental Medicine, Shanghai ...
Geng R   +5 more
doaj  

RORα Suppresses Epithelial-to-Mesenchymal Transition and Invasion in Human Gastric Cancer Cells via the Wnt/β-Catenin Pathway

open access: yesFrontiers in Oncology, 2019
Retinoid-related orphan receptor alpha (RORα) is involved in tumor development. However, the mechanisms underlying RORα inhibiting epithelial-to-mesenchymal transition (EMT) and invasion are poorly understood in gastric cancer (GC).
Jian Su   +24 more
doaj   +1 more source

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