Results 21 to 30 of about 65,682 (262)
The deregulation in the Wnt/β-catenin signaling pathway is associated with many human cancers, particularly colorectal cancer (CRC) and, therefore, represents a promising target for drug development.
Xi Chen +10 more
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Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. [PDF]
The large conductance calcium-activated potassium channel alpha-subunit (Slo) is widely distributed throughout the body and plays an important role in a number of diseases.
Shumin Bian +7 more
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Cinnamaldehyde (CA) is a natural compound that has promising biological activity. The current study investigates the antitumor activity of CA in thioacetamide induced hepatocellular carcinoma (HCC) in rats through targeting the Wnt/β-catenin pathway and ...
Al Shaima G. Abd El Salam +2 more
doaj +1 more source
Obesity is a common disease over the world and is tightly associated with diabetes mellitus, cardiovascular and cancer disease. Although our previous study showed that the synthetic vanadium-protein (V-P) complex had a better effect on antioxidant and ...
Shuang Zhang, Lei Yan, Sang Moo Kim
doaj +1 more source
Involvement of the Wnt/β-catenin signaling pathway in the cellular and molecular mechanisms of fibrosis in endometriosis. [PDF]
BACKGROUND:During the development and progression of endometriotic lesions, excess fibrosis may lead to scarring, chronic pain, and altered tissue function.
Sachiko Matsuzaki, Claude Darcha
doaj +1 more source
Application of on-line nanoLC-IT-TOF in the identification of serum β-catenin complex in mice scald model. [PDF]
Severe burn shock remains an unresolved clinical problem with an urgent need to explore novel therapeutic treatments. Intracellular β-catenin, through interaction with other proteins, has been reported to be able to regulate the size of cutaneous wounds.
Cheng-cai Huang +4 more
doaj +1 more source
Analysis of expression profile of genes encoding cell adhesion proteins in endometrial cancer
Endometrial cancer is one of the most common gynecological malignancies. Unfortunately, molecular pathogenesis of this neoplasm remains poorly understood.
Tomasz Kubiatowski +4 more
doaj +1 more source
Cx43, ZO-1, alpha-catenin and beta-catenin in cataractous lens epithelial cells
Specimens of the anterior lens capsule with an attached monolayer of lens epithelial cells (LECs) were obtained from patients (n=52) undergoing cataract surgery. Specimens were divided into three groups based on the type of cataract: nuclear cataract, cortical cataract and posterior subcapsular cataract (PSC).
Anshul I, Arora +8 more
openaire +2 more sources
Venlafaxine Inhibits the Apoptosis of SHSY-5Y Cells Through Active Wnt/β-Catenin Signaling Pathway
Ruijie Geng,1 Haibin Li,1 Hao Wang,2 Chenyu Ye,1 Yemeng Mao,3 Xiao Huang1,4 1Department of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Teaching Center of Experimental Medicine, Shanghai ...
Geng R +5 more
doaj
Retinoid-related orphan receptor alpha (RORα) is involved in tumor development. However, the mechanisms underlying RORα inhibiting epithelial-to-mesenchymal transition (EMT) and invasion are poorly understood in gastric cancer (GC).
Jian Su +24 more
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