Results 41 to 50 of about 909,137 (164)

Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells

BMC Infectious Diseases, 2006
Background We recently showed that beta-defensins have antimicrobial activity against nontypeable Haemophilus influenzae (NTHi) and that interleukin 1 alpha (IL-1 alpha) up-regulates the transcription of beta-defensin 2 (DEFB4 according to new ...
Park Raekil, Takeshita Tamotsu, Pan Huiqi, Lee Haa-Yung, Moon Sung-Kyun, Cha Kiweon, Andalibi Ali, Lim David J   +7 more
doaj   +1 more source

Modulation of host antimicrobial peptide (beta-defensins 1 and 2) expression during gastritis [PDF]

, 2002
Background: beta-Defensins are a newly identified family of antimicrobial peptides that are expressed by epithelia on mucosal surfaces where their production is augmented by infection or inflammation.
Domizio, P., Bajaj-Elliott, M., Ali, R.S., Domizio, P, Maher, L, Fedeli, P, Farthing, MJG, Fedeli, P., M Bajaj-Elliot (16115810), Quinn, AG, Smith, G.V, Quinn, A.G., Ali, RS, P Domizio (16116209), M J Farthing (16115624), Bajaj-Elliott, M, Maher, L., Farthing, M.J.G., P Fedeli (16116206), R S Ali (16116212), Smith, GV, R G Quinn (16116215), G V Smith (16115678), L Maher (9856208)   +23 more
core   +1 more source

Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms. [PDF]

PLoS ONE, 2010
Defensins are antimicrobial peptides expressed by plants and animals. In mammals there are three subfamilies of defensins, distinguished by structural features: alpha, beta and theta. Alpha and beta-defensins are linear peptides with broad anti-microbial
Aprille Seidel, Ying Ye, Lesley R de Armas, Maira Soto, William Yarosh, Renee A Marcsisin, Dat Tran, Michael E Selsted, David Camerini   +8 more
doaj   +1 more source

Alpha Defensin: A Diagnostic Accuracy Depending on the Infection Definition Used

The Journal of Arthroplasty, 2020
The purpose of this study was to evaluate the alpha defensin qualitative detection (ADLF) sensitivity and specificity as compared with 3 standard classifications in the diagnostic management of chronic prosthetic joint infections.A multicenter cohort of 136 patients with a painful arthroplasty was classified into either infected or noninfected ...
Huard, Maxime, Detrembleur, Christine, Poilvache, Hervé, Pastor y Geels, Ines, Van Cauter, Maïté, Driesen, Ronald, Yombi, Jean Cyr, Neyt, Jeroen, Cornu, Olivier   +8 more
openaire   +3 more sources

Prognostic role of alpha defensin in predicting periprocedural major myocardial injury following elective percutaneous coronary intervention

American Heart Journal Plus
Background: Periprocedural major myocardial injury (pMMI) remains a frequent complication of elective percutaneous coronary intervention (PCI) and is incompletely explained by procedural complexity or ischemic burden alone.
A.A. Higazi, M. Shapira, I. Abumouch, E. Maraga, N. Amsalem, R. Abu Fanne   +5 more
doaj   +1 more source

Identification, Characterization, and Transcriptional Reprogramming of Epithelial Stem Cells and Intestinal Enteroids in Simian Immunodeficiency Virus Infected Rhesus Macaques

Frontiers in Immunology, 2021
Epithelial cell injury and impaired epithelial regeneration are considered key features in HIV pathogenesis and contribute to HIV-induced generalized immune activation.
Nongthombam Boby, Xuewei Cao, Alyssa Ransom, Barcley T. Pace, Christopher Mabee, Monica N. Shroyer, Arpita Das, Peter J. Didier, Sudesh K. Srivastav, Edith Porter, Qiuying Sha, Bapi Pahar, Bapi Pahar, Bapi Pahar   +13 more
doaj   +1 more source

Alpha defensin, leukocyte esterase, C-reactive protein, and leukocyte count in synovial fluid for pre-operative diagnosis of periprosthetic infection

International Journal of Immunopathology and Pharmacology, 2018
Synovial fluid analysis for diagnosis of prosthetic joint infections has gained increasing interest in the recent past when markers more specific for these infections than the serum ones have been identified.
Elena De Vecchi, Carlo Luca Romanò, Roberta De Grandi, Laura Cappelletti, Francesca Villa, Lorenzo Drago   +5 more
doaj   +1 more source

The expression of human alpha and beta defensin in the endometrium and their effect on implantation [PDF]

Journal of Assisted Reproduction and Genetics, 2007
Alpha and beta defensins have been isolated from various human tissues and form an important part of the innate immune system. Their role in implantation of the embryo has not yet been studied. This study was designed to detect both alpha and beta defensins in the mid luteal phase endometrium and investigate the correlation between the defensin ...
S, Das, G S, Vince, I, Lewis-Jones, M D, Bates, R, Gazvani   +4 more
openaire   +2 more sources

Antimicrobial Peptides: Identification of two Beta-Defensins in a Teleost Fish, the European Sea Bass (Dicentrarchus labrax)

Pharmaceuticals, 2021
Beta-defensins consist in a group of cysteine-rich antimicrobial peptides (AMPs), widely found throughout vertebrate species, including teleost fish, with antimicrobial and immunomodulatory activities.
Carolina Barroso, Pedro Carvalho, José F. M. Gonçalves, Pedro N. S. Rodrigues, João V. Neves   +4 more
doaj   +1 more source

Sequence analysis of a 212 kb defensin gene cluster on ECA 27q17

, 2006
Defensins are a family of evolutionary ancient antimicrobial peptides consisting of three sub-families: alpha-, beta- and theta-defensins. This investigation was focused on the genomic characterization of equine beta-defensins and the investigation of ...
Paul, Sven, Kuiper, Heidi, Looft, Christian, Distl, Ottmar, Chowdhary, Bhanu P, Leeb, Tosso, Philipp, Ute, Regenhard, Petra   +7 more
core   +1 more source