Results 1 to 10 of about 10,851 (203)

Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]

open access: yesActa Poloniae Pharmaceutica, 2023
The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri   +2 more
doaj   +1 more source

DETERMINATION OF CENTRAL NERVOUS EFFECT AND ANTIDOTAL EFFECT AGAINST CHLORPYRIFOS TOXICITY OF ALPHA-LIPOIC ACID THROUGH PHARMACOLOGICAL AND TOXICOLOGICAL CHALLENGES

open access: yesSVU-International Journal of Veterinary Sciences, 2022
Background: Pharmacological and toxicological challenges are among the most important studies in revealing the latent properties of drugs Objective: the goal of this study was to evaluate the effects of alpha-lipoic acid on the central nervous system ...
Marwa Abdul-Ghani, Ahmed Naser
doaj   +1 more source

The protective impacts of lipoic acid on diclofenac-induced hepatorenal toxicity in broiler chicks [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2022
Alpha-lipoic acid is an anti-inflammatory and antioxidant compound that shows free radical scavenging actions and potent antioxidant properties on the metabolites of other cellular oxidants.
Marwa R. Abdul-Ghani, Ahmed S. Naser
doaj   +1 more source

Alpha-Lipoic Acid as a Nutritive Supplement for Humans and Animals: An Overview of Its Use in Dog Food

open access: yesAnimals, 2021
Alpha-lipoic acid (a-LA) is used as a nutritive additive in dog food. Therefore, we performed a systematic review of studies published to date in PubMed, Google Scholar, Cochrane Library and MedlinePlus involving alpha-lipoic acid supplementation, which ...
Reshma M. Anthony   +2 more
doaj   +1 more source

Effect of Alpha-Lipoic Acid on the Characteristics and Physical Stability of NLC-Green Tea Extract

open access: yesJurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022
Background: The addition of alpha-lipoic acid in Nanostructured Lipid Carrier-Green Tea Extract (NLC-GTE) has potential to increase effectiveness of anti-aging preparations.
Fairuz Yaumil Afra   +2 more
doaj   +1 more source

Estimation of pharmacokinetic parameters of alpha-lipoic acid in the chicks model

open access: yesBaghdad Journal of Biochemistry and Applied Biological Sciences, 2022
Background and objective: Alpha-lipoic acid is a drug used to treat diabetic neuropathy, and it has other uses as a dietary supplement. The target of the study was to investigate the concentration of therapeutic doses of Alpha-lipoic acid in the blood ...
Marwa R. Abdulghani, Ahmed S. Naser
doaj   +1 more source

The role of information service in rational pharmacotherapy with thioctic acid in patients in Preferential Medicinal Providing

open access: yesКачественная клиническая практика, 2021
Rational pharmacotherapy in the Program of Preferential Medicinal Providing can be implemented subject to high-quality information support from healthcare professionals.
E. V. Eliseeva   +4 more
doaj   +1 more source

Activity of serum paraoxonase 1, lipid profile and atherogenic indexes in diabetic induced rats treated with alpha lipoic acid [PDF]

open access: yesJournal of Nephropathology, 2018
Background: Paraoxonase 1 (PON1) is an enzyme attached to high density lipoprotein (HDL-C) which has antioxidant and anti-atherogenic activities. Objectives: In this study, we investigated the effects of alpha lipoic acid on PON1 activity, lipid profile ...
Parisa Jamor   +3 more
doaj   +1 more source

Alpha-Lipoic Acid Is an Effective Nutritive Antioxidant for Healthy Adult Dogs

open access: yesAnimals, 2021
This study was designed to determine the effect of alpha-lipoic acid on the glutathione status in healthy adult dogs. Following a 15 month baseline period during which dogs were fed a food containing no alpha-lipoic acid, dogs were randomly allocated ...
Reshma M. Anthony   +4 more
doaj   +1 more source

Neuroprotective Effects of Alpha Lipoic Acid on Haloperidol-Induced Oxidative Stress in the Rat Brain

open access: yesCell & Bioscience, 2011
Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role of reactive oxygen species in inducing ...
Perera Joachim   +4 more
doaj   +1 more source

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