Results 251 to 260 of about 27,057 (295)
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The Netherlands Journal of Medicine, 2010
Background: Neuropathic pain is difficult to treat. We identified those studies in the literature in which the effectiveness of alpha lipoic acid as a treatment for neuropathic pain was evaluated.Methods: Systematic literature review. The databases MEDLINE and EMBASE were searched using the keywords "lipoic acid", "thioctic acid", "diabet*", and the ...
Mijnhout, G. S. +3 more
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Background: Neuropathic pain is difficult to treat. We identified those studies in the literature in which the effectiveness of alpha lipoic acid as a treatment for neuropathic pain was evaluated.Methods: Systematic literature review. The databases MEDLINE and EMBASE were searched using the keywords "lipoic acid", "thioctic acid", "diabet*", and the ...
Mijnhout, G. S. +3 more
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The effects of alpha-lipoic acid on diabetic myopathy
Journal of Endocrinological Investigation, 2017Increased oxidative stress and impaired antioxidant defense are important mechanisms in the pathogenesis of diabetic myopathy. Since diabetes mellitus type 1 decreases muscle regeneration capacity the present study was designed to determine the influence of alpha-lipoic acid (ALA), a potent biological antioxidant, on the process of regeneration of ...
Jurišić Eržen, Dubravka +5 more
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Alpha-lipoic acid in the treatment of diabetic polyneuropathy
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and ...
E I, Chukanova, A S, Chukanova
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Antiplatelet Activity of α-Lipoic Acid
Journal of Agricultural and Food Chemistry, 2010Alpha-lipoic acid (ALA) is often used as a dietary supplement to prevent and treat chronic diseases associated with excessive oxidative stress. The aim of this study was to investigate the mechanisms of the antiplatelet activity of ALA. ALA significantly inhibited collagen-induced platelet aggregation, thromboxane B(2) (TXB(2)) formation, Ca(2 ...
Yuan-Shu, Lai +3 more
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Alpha lipoic acid: a novel treatment for depression
Medical Hypotheses, 2000Insulin resistance has been associated with people diagnosed with depression. Conversely, it has also been documented that diabetics have an increased risk of depression. Evidence suggests that insulin activity plays a role in serotonergic activity by increasing the influx of tryptophan into the brain. This increased influx of tryptophan has been shown
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Biochemistry and molecular biology international, 1997
Due to its strained five-membered ring, alpha-lipoic acid (LA) has an absorption band around 330 nm, which is used to quantify its concentration. In order to obtain information for the homolytic rupture of the S-S bond and the formation of dihydrolipoic acid (DHLA), the photochemical reaction of lipoic acid was examined in the presence or absence of ...
S, Matsugo +3 more
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Due to its strained five-membered ring, alpha-lipoic acid (LA) has an absorption band around 330 nm, which is used to quantify its concentration. In order to obtain information for the homolytic rupture of the S-S bond and the formation of dihydrolipoic acid (DHLA), the photochemical reaction of lipoic acid was examined in the presence or absence of ...
S, Matsugo +3 more
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Oxidation of .alpha.-lipoic acid
The Journal of Organic Chemistry, 1975F E, Stary, S J, Jindal, R W, Murray
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Alpha Lipoic Acid for Schizophrenia
Journal of Clinical Psychopharmacology, 2023Taro Kishi +6 more
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Alpha-lipoic acid: The metabolic antioxidant
Free Radical Biology and Medicine, 1996L, Packer, H J, Tritschler
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