Results 21 to 30 of about 10,851 (203)
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2020 Diabetic neuropathy (DN) is the most common chronic complication of diabetes mellitus. Hyperglycemia-induced oxidative stress induces programmed cell death of nerves, which contributes to the pathology of Diabetic neuropathy. Many clinical trials depend
Rusul AbdulKareem Hadi +2 more
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Drug Design, Development and Therapy, 2020 Giuseppe Derosa,1,2 Angela D’Angelo,2 Paola Preti,1 Pamela Maffioli1 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 2Laboratory of Molecular Medicine, University of Pavia, Pavia, ItalyCorrespondence: Giuseppe ...
Derosa G +3 more
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A dual action of alpha-lipoic acid in the brain: an electrophysiological evaluation [PDF]
Arquivos de Neuro-Psiquiatria, 2003 Oxidative stress causes metabolic and structural abnormalities during reperfusion. In an animal model of electrophysiological evaluation of cerebral ischemia-reperfusion, alpha-lipoic acid effect on the oxidative stress was studied by mean absolute ...
Otoni Cardoso do Vale +3 more
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Clinical Approaches to the Treatment of Diabetic Neuropathy
Mìžnarodnij Endokrinologìčnij Žurnal, 2014 The article is devoted to the treatment of diabetic neuropathy. The described scheme of application of preparations of alpha-lipoic (thioctic) acid. Recently in Europe and the United States conducted a series of clinical studies that have shown that the ...
A.V. Kaminsky
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Journal of Diabetes Research, 2015 After evaluating the prevalence of early endothelial dysfunction, as measured by means of reactive hyperemia in adolescents with type 1 diabetes, we started a 6-month, double-blind, randomized trial to test the efficacy of an antioxidant diet (± alpha ...
Andrea Scaramuzza +8 more
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α-Lipoic Acid and Cardiovascular Disease [PDF]
The Journal of Nutrition, 2003 Alpha-lipoic acid (ALA) has been identified as a powerful antioxidant found naturally in our diets, but appears to have increased functional capacity when given as a supplement in the form of a natural or synthetic isolate. ALA and its active reduced counterpart, dihydrolipoic acid (DHLA), have been shown to combat oxidative stress by quenching a ...
Stephanie D, Wollin, Peter J H, Jones
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Anticholesterol Activity of α-Lipoic Acid [PDF]
Nature, 1958 SINCE α-lipoic acid is known to affect lipid metabolism, we have investigated the effect of this acid on the lipid content of plasma, liver and aorta from rabbits which had been fed on a diet containing an excess of cholesterol1. Rabbits weighing 2.5–3 kgm. were divided into four groups, each containing five animals.
L, ANGELUCCI, E, MASCITELLI-CORIANDOLI
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Mìžnarodnij Endokrinologìčnij Žurnal, 2012 The article deals with one of most common complications of diabetes mellitus — diabetic polyneuropathy. It is proved that alpha-lipoic acid is a drug of pathogenetic treatment of such pathology.
O.V. Bolshova, O.Ya. Samson
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Encapsulation of α-lipoic acid intochitosan and alginate/gelatin hydrogel microparticles and its in vitro antioxidant activity [PDF]
Hemijska Industrija, 2016 Alpha-lipoic acidis an organosulphur compound well-known for its therapeutic potential and antioxidant properties. However, the effective use of α-lipoic acid depends on biological plasma half-life and its preserving stability, which could be ...
Vidović Bojana B. +6 more
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Advanced Science, EarlyView.Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He +8 more
wiley +1 more source