Results 61 to 70 of about 10,851 (203)

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

Evaluating the protective effect of resveratrol, Q10, and alpha-lipoic acid on radiation-induced mice spermatogenesis injury: A histopathological study

open access: yesInternational Journal of Reproductive BioMedicine, 2019
Background Testis is one of the most sensitive organs against the toxic effect of ionizing radiation. Exposure to even a low dose of radiation during radiotherapy, diagnostic radiology, or a radiological event could pose a threat to spermatogenesis.
Masoud Najafi   +5 more
doaj   +1 more source

Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment

open access: yesСахарный диабет, 2011
Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods.
Tatiana Yul'evna Demidova   +1 more
doaj   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

open access: yesCell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang   +12 more
wiley   +1 more source

The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy

open access: yesBasic and Clinical Neuroscience, 2012
Introduction : Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory.
Narges Karimi   +3 more
doaj   +2 more sources

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian   +2 more
wiley   +1 more source

Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials

open access: yesInternational Journal of Endocrinology, 2012
Objective. We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus. Research design and methods.
Gerritje S. Mijnhout   +4 more
doaj   +1 more source

The effect of antioxidants in acute amitriptyline poisoning

open access: yesToxicology Reports, 2019
Objective: To study the effect of Antioxidants supplementation in reducing oxidative stress induced in acute amitriptyline poisoning cases. Design and methods: We compared the effect of supplementation of treatment of acute amitriptyline poisoning cases ...
S. Hameed Kadar Ali, Wasim Ali Raja
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

Role of Alpha Lipoic Acid in Oxidant /Antioxidant Status and Gene Expression of Glutathione Reductase in Hydrogen Peroxide Exposed Rats: (Part -2)

open access: yesThe Iraqi Journal of Veterinary Medicine, 2019
This study was designated to evaluate the protective role of alpha lipoic acid against oxidative stress resulted by hydrogen peroxide on some oxidants/ antioxidants  parameters and gene expression of glutathione peroxidase in  adult Wistar rats.
Baraa Najim Al-Okialy
doaj   +1 more source

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