Results 81 to 90 of about 27,057 (295)

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]

, 2016
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina, De Santis, Stefano, Fulvi, Alberto, Giovannoni, Daniele, Marcassa, Claudio, Migliorino, Maria Rita, Ricciardi, Serena   +6 more
core   +2 more sources

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Alpha-lipoic acid for diabetic peripheral neuropathy. [PDF]

Cochrane Database Syst Rev, 2018
Diabetic peripheral neuropathy (DPN) is a frequent complication in people living with type 1 or type 2 diabetes. There is currently no effective treatment for DPN. Although alpha-lipoic acid (ALA, also known as thioctic acid) is widely used, there is no consensus about its benefits and harms.To assess the effects of alpha-lipoic acid as a disease ...
Baicus C, Purcarea A, von Elm E, Delcea C, Furtunescu FL.   +4 more
europepmc   +5 more sources

Endothelial dysfunction in type 2 diabetes: effect of antioxidants [PDF]

, 2007
Individuals with insulin resistance and diabetes mellitus have increased cardiovascular morbidity and mortality, caused in part by vascular complications. Endothelial dysfunction has been implicated in the pathogenesis of vascular diabetic disease.
Louro, T, Nunes, E, Proença, T, Seiça, RM, Sena, CM   +4 more
core  

New advances in the in-vitro culture of Dientamoeba fragilis [PDF]

, 2012
Dientamoeba fragilis is an intestinal protozoan in humans that is commonly associated with diarrhoea and other gastrointestinal complaints. Studies conducted to investigate the biology of this parasite are limited by methods for in vitro cultivation. The
Ellis, JT, Munasinghe, VS, Stark, D
core   +1 more source

ALPHA LIPOIC LIPOIC ACID IN CLINICAL ACID IN CLINICAL APPLICA APPLICATION

Praxis medica, 2009
<p>Alpha lipoic acid is the most efficient of all known antioxidants for its lipo and hydrosolubility which enable easy penetrability in cytoplasm making its protection of free reactive radicals, energetic metabolism, regulation of genetic expresion etc.
B. Vučinić, R. Mitić, S. Dimić, Z. Milanović, S. Sovtić   +4 more
openaire   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Dihydrolipoic acid reduces cytochrome b561 proteins. [PDF]

, 2013
Cytochrome b561 (Cyt-b561) proteins constitute a family of trans-membrane proteins that are present in a wide variety of organisms. Two of their characteristic properties are the reducibility by ascorbate (ASC) and the presence of two distinct b-type ...
A Bast, A Bérczi, A Bérczi, A Bérczi, A Bérczi, A Bérczi, A Glanfield, A Mizutani, AA Herbert, Alajos Bérczi, AT McKie, AV Kozlov, C Sgherri, D Griesen, D Han, D Zhang, E Okuyama, ELR Stokstad, ER Henry, F Desmet, GE Tusnády, GE Tusnády, GP Biewenga, GP Biewenga, H Asard, H Kataoka, H Scholich, Han Asard, J Lykkesfeldt, JCH Shih, JS Oakhill, L Cenacchi, L Packer, L Packer, L Packer, L Zimányi, LJ Reed, László Zimányi, M Lakshminarasimhan, M Srivastava, M Tsubaki, M Tsubaki, MAK Markwell, MC Recuenco, O Terland, PJ Fleming, PM Kelley, R Yasuno, RI Shrager, S Ludwiczek, SJ Booker, T Flatmark, TW Nichols, U Pérez-López, UM Kent, V Preger, VE Kagan, W Liu, W Liu, W Verelst, Y Li, Y Nanasato   +61 more
core   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source