Results 71 to 80 of about 3,275,969 (247)

Alpha-lipoic acid, an anti-obesity agent?

open access: yes, 2004
Obesity shortens life expectancy and is a risk factor for hypertension and Type 2 diabetes. When added to the standard chow of Sprague-Dawley or Otsuka Long-Evans Tokushima Fatty rats, alpha-lipoic acid (0.5% weight/weight) reduced body weight and food ...
Doggrell, Sheila A
core   +1 more source

Ameliorative Effect of Alpha Lipoic Acid on Endometriosis: An Experimental Model in Rats

open access: yes, 2020
Aim:This study aims to evaluate the effects of alpha lipoic acid (ALA), which is a strong antioxidant, on endometriosis (EMS).Methods:Thirty sexually-mature, female Wistar albino rats weighing 180-220 grams were separated into three groups: sham (n=10 ...
Taylan Onat, Murat Çakır
core   +1 more source

Transformative Masked Ortho‐Quinone Chemistry: From Direct Guaiacol Activation to Lignin‐Based Adhesives

open access: yesAngewandte Chemie International Edition, EarlyView.
Renewable guaiacols are rapidly oxidized by phenyliodine(III)diacetate to masked ortho‐quinones, giving a new class of monomers that undergo selective Michael‐type polyaddition with multithiols to from thiol‐guaiacol connectivity‐bearing polymers. The activation applies to discrete monomers and directly to lignin, enabling two‐component adhesives that ...
Dominik P. Hoch   +7 more
wiley   +1 more source

The effect of alpha-lipoic acid on mitochondrial superoxide and glucocorticoid-induced hypertension [PDF]

open access: yes, 2016
Aims. To examine the effect of alpha-lipoic acid, an antioxidant with mitochondrial superoxide inhibitory properties, on adrenocorticotrophic hormone- (ACTH-HT) and dexamethasone-induced hypertensions (DEX-HT) in rats and if any antihypertensive effect ...
Ong, Lee Lin (Sharon)   +4 more
core   +1 more source

Alpha-lipoic acid for diabetic peripheral neuropathy

open access: yesCochrane Database of Systematic Reviews, 2018
Diabetic peripheral neuropathy (DPN) is a frequent complication in people living with type 1 or type 2 diabetes. There is currently no effective treatment for DPN. Although alpha-lipoic acid (ALA, also known as thioctic acid) is widely used, there is no consensus about its benefits and harms.To assess the effects of alpha-lipoic acid as a disease ...
Baicus, Cristian   +4 more
openaire   +4 more sources

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

The use of rosuvastatin and alpha lipoic acid in patients with unstable angina

open access: yesActa Medica Leopoliensia, 2017
Aim. To investigate the blood lipid profile, indices of functional condition of the liver in patients with unstable angina in the treatment of statins in combination with alpha lipoic acid.  Material and Methods.
E.H. Zaremba   +3 more
doaj   +1 more source

Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment [PDF]

open access: yes, 2011
Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods.
Yulia Alexandrovna Trakhtenberg   +1 more
core   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

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