Results 71 to 80 of about 10,851 (203)

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador   +5 more
wiley   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

ALPHA-LIPOIC ACID – EFFECTS AND APPLICATIONS

open access: yes, 2023
Alpha-lipoic acid is one of the most powerful antioxidants used in both humans and animals. Many of its effects were proven: antioxidant, antidiabetic, anti-inflammatory, immunomodulatory, analgesic, as a growth promoter. Numerous clinical studies showed the effectiveness of alpha-lipoic acid in diseases in which the antioxidant balance was disturbed ...
openaire   +1 more source

Gene Editing and Transformation Strategies for Engineering Drought‐Tolerant Legumes

open access: yesLegume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Legumes play a vital role in agriculture, nutrition, and the economy, but their production faces significant threats. Among these, drought and its unpredictability will be the most damaging constraint in the coming decades. Enhancing drought tolerance is essential for resilient and sustainable legume cultivation, and genetic engineering ...
Andrea Fernandez‐Gutierrez   +2 more
wiley   +1 more source

Alpha-lipoic acid induced insulin autoimmune antibody syndrome

open access: yesThe Egyptian Journal of Internal Medicine
Background Insulin autoimmune antibody syndrome is an uncommon cause of hypoglycemia in non-diabetic individuals. We report a case of alpha-lipoic acid-induced insulin autoimmune antibody syndrome.
Karthik Baburaj, Jabir MP, Vimal MV
doaj   +1 more source

Clinical effect of alpha-lipoic acid plus high flux hemodialysis on peripheral neuropathy in patients with diabetic hemodialysis

open access: yesLinchuang shenzangbing zazhi, 2021
Objective To explore the clinical effect of alpha-lipoic acid plus high flux hemodialysis on diabetics with peripheral neuropathy.Methods A total of 60 patients with diabetic hemodialysis and peripheral neuropathy were selected from 2016 to 2019.They ...
Shao Ning   +8 more
doaj  

From Light‐Driven to Dark Synthesis: Streamlining Perfluoroalkyl Selenide Ether Formation

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 5, 7 February 2026.
Two orthogonal and user‐friendly protocols enable the efficient construction of (Se/S)RF bonds from simple dichalcogenides and perfluoroalkyl iodides. Visible‐light irradiation at 395 nm promotes seleno‐ and thioether formation, while a dark KOH/MeCN variant delivers selenoethers in minutes. Both approaches operate under mild, metal‐ and photocatalyst‐
Loydel Torres Barroso   +5 more
wiley   +1 more source

Effects of Alpha Lipoic Acid Supplementation on Slow Skeletal Muscle Mass and Contractile Functions in Type 2 Diabetic Male Sprague Dawley Rats

open access: yesLife and Science
Objective: To see the Effects of Alpha-Lipoic Acid (ALA) supplementation on slow skeletal muscle mass and contractile functions in type 2 diabetic male Sprague Dawley rats. Study Design: Quasi-experimental study.
Barkat Ullah Khan   +5 more
doaj   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

open access: yesAdvanced Science, Volume 13, Issue 12, 27 February 2026.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men   +7 more
wiley   +1 more source

The investigation of effect of alpha lipoic acid against damage on neonatal rat lung to maternal tobacco smoke exposure

open access: yesToxicology Reports, 2018
This study was carried out to determine the changes in the lungs of the rat pups exposed to tobacco smoke during pregnancy period and to investigate the protective effects of alpha lipoic acid, which is administered during pregnancy, on these changes ...
Elif Erdem Guzel   +5 more
doaj   +1 more source

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